Topicort Spray Coupons & Prices

Desoximetasone

Topicort Spray is a topical corticosteroid that is used to treat plaque psoriasis in adults. Topicort Spray helps reduce symptoms of plaque psoriasis, such as redness, itching, and swelling. Desoximetasone topical spray is the generic version of Topicort Topical Spray. The average price of Topicort Spray is $657.08. You may be able to save on the retail price of this medication with a SingleCare Topicort Spray coupon or discount card. SingleCare coupons and savings cards are accepted at drugstores across the United States. The lowest price for Topicort Spray with a free discount card from SingleCare is currently $69.60 at participating pharmacies.

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0.1 spray btl100ml of 0.25%Edit

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Topicort Spray coupon at CVS Pharmacy
$72.60
$ 69.60
$3 off with signupwith signup

Show this free card to your pharmacist.

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Topicort Spray coupon at Walgreens Pharmacy
$87.37
$ 84.37
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Topicort Spray coupon at Publix Pharmacy
$99.18
$ 96.18
$3 off with signupwith signup
Topicort Spray coupon at Walmart Neighborhood Market Pharmacy
$145.25
$ 142.25
$3 off with signupwith signup
Topicort Spray coupon at Walmart Pharmacy
$145.25
$ 142.25
$3 off with signupwith signup
Topicort Spray coupon at Food Lion Pharmacy
$ 146.25
$150.13
$ 147.13
$3 off with signupwith signup
$150.13
$ 147.13
$3 off with signupwith signup
$ 148.25

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/21/2025

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4.8 average rating
About Topicort Spray

Topicort Spray is a topical corticosteroid that is used to treat plaque psoriasis in adults. Topicort Spray helps reduce symptoms of plaque psoriasis, such as redness, itching, and swelling. Desoximetasone topical spray is the generic version of Topicort Topical Spray. The average price of Topicort Spray is $657.08. You may be able to save on the retail price of this medication with a SingleCare Topicort Spray coupon or discount card. SingleCare coupons and savings cards are accepted at drugstores across the United States. The lowest price for Topicort Spray with a free discount card from SingleCare is currently $69.60 at participating pharmacies.

Topicort Spray Price History & Information

Price History for Topicort Spray (Brand) & Desoximetasone (Generic)

1 count, spray btl, 100ml of 0.25%

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Topicort Spray (Brand) & Desoximetasone (Generic)

1 count, spray btl, 100ml of 0.25%
PharmacyDesoximetasone Retail PriceDesoximetasone SingleCare Price
Walgreens$432.00$243.00
Kroger Pharmacy$173.00$150.00

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Topicort Spray

Topicort Spray is a topical corticosteroid that is used to treat plaque psoriasis in adults. Topicort Spray helps reduce symptoms of plaque psoriasis, such as redness, itching, and swelling. Desoximetasone topical spray is the generic version of Topicort Topical Spray. The average price of Topicort Spray is $657.08. You may be able to save on the retail price of this medication with a SingleCare Topicort Spray coupon or discount card. SingleCare coupons and savings cards are accepted at drugstores across the United States. The lowest price for Topicort Spray with a free discount card from SingleCare is currently $69.60 at participating pharmacies.

Topicort Spray FAQs

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

How much does Topicort Spray cost without insurance?

You could pay a cash price as high as $657.08 on Topicort Spray without insurance. With a SingleCare prescription savings card, you may pay just $69.60 for a standard supply. You could also ask your doctor or pharmacist about desoximetasone topical spray, the generic version of Topicort Spray, which may be cheaper than the brand name. SingleCare has coupons for both.

How much does Topicort Spray cost with insurance?

The cost of Topicort Spray with insurance can vary by insurance plan and provider; however, Topicort Spray usually retails for $657.08. With a SingleCare coupon for Topicort Spray, you could pay as little as $69.60 for this prescription drug. During your next visit to your local pharmacy, ask your pharmacist to compare the price with insurance coverage to the price with a SingleCare discount.

Does Medicare cover Topicort Spray and how much does it cost?

Some Medicare plans may help cover Topicort Spray, which is a relatively expensive brand-name prescription drug. Check with your plan to determine what your potential copay may be. To save on the cost of your refills, you could use a SingleCare prescription discount card at participating pharmacies and pay a reduced price of $69.60 for Topicort Spray. Stop in at your nearest participating pharmacy and start saving with SingleCare.

Is there a generic of Topicort Spray?

Topicort Spray is a brand-name prescription medication that is manufactured by Taro Pharmaceuticals. Desoximetasone topical spray is the generic version of Topicort Spray.

What is Topicort Spray?

Topicort Spray is a topical steroid that is used to treat plaque psoriasis. As a corticosteroid, Topicort Spray works by reducing inflammation. It can help treat the symptoms of plaque psoriasis, such as redness, itching, and swelling. 

You should only use Topicort Spray precisely as prescribed by a doctor. You should not use it on your face, groin area, or underarms unless your doctor has said so. You should also avoid getting this medication in your eyes, mouth, or vagina; if you do, you should rinse the affected area thoroughly with water.

You should apply Topicort Spray with clean, dry hands. You should leave the affected area uncovered unless your doctor directs you to do otherwise. 

You should tell your healthcare provider about any medical conditions you may have or other medications you’re taking, including over-the-counter medications and herbal supplements, before using Topicort Spray. You should not use Topicort Spray if you are allergic to any of its ingredients or other corticosteroids.

Topicort Spray is flammable so you should avoid smoking when applying this medication. You should also avoid storing this medication close to an open flame.

If your condition does not improve after four weeks, you should get immediate medical advice from your doctor. The manufacturer of Topicort Spray advises against the use of this product for longer than four weeks.

What are the side effects of Topicort Spray?

The most common side effects of Topicort Spray include irritation, itching, and dryness around where the medication is applied. Other possible side effects include changes in the skin, such as stretch marks, skin thinning, discoloration, and acne. 

Rare but serious side effects may include adrenal gland problems, Cushing’s syndrome, increased blood sugar levels, glaucoma, and cataracts. Talk to a doctor if you experience any side effects while using Topicort Spray. 

This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions. You can report negative side effects to the FDA.

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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Where are Topicort Spray coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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