Synthroid (levothyroxine) is used to treat an underactive thyroid (hypothyroidism). It helps supplement thyroid hormone when thyroid hormone levels are too low. It can also be used to manage thyroid cancer. The thyroid hormone is important for maintaining essential functions of the body, such as metabolism. Synthroid is a brand-name medication that can have an average cost of $207.97 for 90, 75mcg tablets. To save money on your prescription or refill, you may be able to use a coupon from SingleCare to purchase generic Synthroid for $10.00 for 90, 75mcg tablets.
Edit your dosage
14 tablet, 25mcgEdit
Unlock members-only prices.Free signup.
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.

Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Synthroid (levothyroxine) is used to treat an underactive thyroid (hypothyroidism). It helps supplement thyroid hormone when thyroid hormone levels are too low. It can also be used to manage thyroid cancer. The thyroid hormone is important for maintaining essential functions of the body, such as metabolism. Synthroid is a brand-name medication that can have an average cost of $207.97 for 90, 75mcg tablets. To save money on your prescription or refill, you may be able to use a coupon from SingleCare to purchase generic Synthroid for $10.00 for 90, 75mcg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Synthroid Retail Price | Levothyroxine Sodium Retail Price | Levothyroxine Sodium SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $200.70 | $35.10 | $35.10 |
| Walmart | $171.18 | $24.81 | $22.56 |
| Walgreens | $266.78 | $35.54 | $24.23 |
| Kroger Pharmacy | $285.58 | $36.65 | $15.30 |
| Albertsons Pharmacy | $197.10 | $50.40 | $17.10 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Synthroid (levothyroxine) is used to treat an underactive thyroid (hypothyroidism). It helps supplement thyroid hormone when thyroid hormone levels are too low. It can also be used to manage thyroid cancer. The thyroid hormone is important for maintaining essential functions of the body, such as metabolism. Synthroid is a brand-name medication that can have an average cost of $207.97 for 90, 75mcg tablets. To save money on your prescription or refill, you may be able to use a coupon from SingleCare to purchase generic Synthroid for $10.00 for 90, 75mcg tablets.
Synthroid is a brand-name drug that contains the active ingredient levothyroxine sodium. Generic levothyroxine is available for purchase. Generic drugs are usually cheaper than their brand-name counterparts. You can ask your healthcare provider if you can take the generic version.
Levothyroxine is the generic name and active ingredient of Synthroid (a brand-name medication manufactured by AbbVie Inc.). Other brand names for levothyroxine include Levoxyl, Unithroid, and Tirosint. These medications function similarly, but dosages, side effects, and drug interactions may differ. Your healthcare provider can help determine which thyroid medication is best for you.
Synthroid helps supplement thyroid hormone in people with hypothyroidism. It can also be used to help manage thyroid cancer. The thyroid hormone is essential for several functions in the body, including regulating metabolism, controlling heart rate, and managing muscle, brain, and bone development. Fatigue, constipation, dry skin, weight gain, slow heartbeat, and sensitivity to cold are some symptoms of low thyroid hormone levels. Your healthcare provider can order blood work to check your thyroid levels.
The appropriate dosage of Synthroid should be personalized and determined by a healthcare provider. Tell your healthcare provider if you continue to experience symptoms of hypothyroidism while taking Synthroid. Your dosage may need to be adjusted.
Synthroid is approved for use in children and adults. It is usually taken daily on an empty stomach, around 30 minutes to one hour before breakfast. Eating too soon after taking Synthroid could interfere with the amount of thyroid hormone the body is able to absorb.
Thyroid medication can be expensive depending on which drug you're prescribed, your insurance coverage, and whether you qualify for additional financial assistance. However, the most influential factor in thyroid medication costs is the fact that thyroid treatment is a lifelong treatment.
If you are prescribed a brand-name drug, ask your healthcare provider if there is a cheaper, generic version available that you can take. Brand-name drugs are usually more expensive than generic drugs.
To save on your prescription, you can also search the SingleCare website or app for drug coupons. These coupons could save you up to 80% on your prescriptions.
Synthroid is available as a 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, or 300 mcg oral tablet. The dosage prescribed by a healthcare provider depends on several factors, such as age, body weight, other medical conditions you have, and other medications you’re taking. It may take four to six weeks of treatment to experience maximum benefits.
For children who are unable to swallow tablets, the tablet may be crushed and mixed with one to two teaspoons of water. The medicine can then be administered orally right away through a dropper or spoon. Synthroid should not be mixed with infant formula unless permitted by your child's pediatrician.
Always follow your healthcare provider's instructions and medical advice when taking or administering this medication. Synthroid is typically prescribed as a long-term or lifelong treatment. Routine lab tests may be needed to monitor how well the medication is working for you.
Before taking Synthroid, discuss your current list of medications with your doctor. These include prescription medications, over-the-counter products, and even herbal supplements. Some medications, like antacids and diet supplements, can interfere with your body's absorption of the thyroid hormone.
Side effects that occur with Synthroid usually develop as a result of hyperthyroidism or too much thyroid hormone in the body. Symptoms of hyperthyroidism include heart rhythm irregularities (arrhythmias), shortness of breath, headache, nervousness, irritability, insomnia, tremors, increased appetite, weight loss, diarrhea, and heat intolerance. You might also experience temporary hair loss in the first few months of taking Synthroid, but this side effect should subside as your body adjusts to the medication.
Allergic reactions are a rare but possible side effect of Synthroid. Signs and symptoms of an allergic reaction include itching, rash, flushing, fever, and shortness of breath. Seek immediate medical attention if you experience signs or symptoms of an allergic reaction. Other serious side effects of Synthroid include heart attack, adrenal problems, changes in blood sugar, and changes in bone density.
This is not a complete list of side effects. Talk to a healthcare professional about other possible side effects, warnings, and drug interactions.
A change in appetite is a possible side effect of Synthroid. An increase in appetite is more likely to occur than a decrease in appetite with Synthroid. An increase in appetite may be caused by high doses of Synthroid, so consult with your healthcare provider if you experience any unusual changes in appetite. How Synthroid affects your appetite depends on your thyroid hormone levels, the dosage of your Synthroid prescription, and how you respond to the medication.
Low thyroid hormone levels can slow metabolism, which may lead to weight gain. This is why people with an underactive or inactive thyroid commonly experience weight gain. Treatment for hypothyroidism balances thyroid hormone levels, which may result in weight loss for some people. However, Synthroid is not used as a weight-loss drug. Taking larger doses of Synthroid than normal may cause serious side effects.
For some people, weight gain is a possible side effect of Synthroid. Weight gain could result from an increase in appetite after taking Synthroid.
Without insurance, you could pay around $207.97 for 90, 75mcg tablets for a prescription of Synthroid. The actual cash price of Synthroid can vary based on the strength, dosage, and quantity prescribed. Synthroid prices may also vary based on your pharmacy and location. You may be able to get a discount off the retail price of Synthroid and other prescription drugs by using a SingleCare discount card at a participating pharmacy. For Synthroid, you could pay only $10.00 for 90, 75mcg tablets with SingleCare.
Synthroid copays vary by insurance plan, so you'll have to ask your pharmacist or insurance plan’s provider to determine your cost with insurance coverage. The cost of Synthroid with insurance can also depend on your deductible and the insurance plan’s formulary. If you don’t have enough coverage with insurance, you could use a SingleCare savings card at checkout rather than paying with insurance. Compare SingleCare's lowest price of $10.00 for 90, 75mcg tablets of Synthroid to your out-of-pocket costs with insurance. SingleCare Synthroid coupons could save you more money than your healthcare plan.
Medicare may help cover the cost of Synthroid, although insurance plans typically prefer to cover the generic version of Synthroid, levothyroxine. You could still owe some money out of pocket, though. Consult with your pharmacist or Medicare plan’s provider to determine your copay for Synthroid.
You can also ask your pharmacist to compare your Synthroid cost with Medicare coverage to your cost with a SingleCare savings card. In some cases, you might find that SingleCare saves you more than Medicare.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved