Symbyax Coupons & Prices

Symbyax is a brand-name combination prescription drug used to treat depressive episodes in bipolar disorder (manic-depressive illness) as well as severe depression that does not respond to other medications. Symbyax combines an SSRI, fluoxetine, which treats depression, with an antipsychotic, olanzapine, which treats psychosis and mania. On average, the retail price of Symbyax is $367.47, but only costs $75.03 with a SingleCare Symbyax coupon. Many local pharmacies—CVS, Target, Longs Drugs, Walgreens, and Duane Reade—accept SingleCare.

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Symbyax coupon at CVS Pharmacy
$78.03
$ 75.03
$3 off with signupwith signup

Show this free card to your pharmacist.

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Symbyax coupon at Walmart Neighborhood Market Pharmacy
$108.62
$ 105.62
$3 off with signupwith signup

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Symbyax coupon at Walmart Pharmacy
$108.62
$ 105.62
$3 off with signupwith signup
Symbyax coupon at Walgreens Pharmacy
$136.69
$ 133.69
$3 off with signupwith signup
Symbyax coupon at Publix Pharmacy
$170.23
$ 167.23
$3 off with signupwith signup
Symbyax coupon at Food Lion Pharmacy
$ 180.25
$184.14
$ 181.14
$3 off with signupwith signup
$184.14
$ 181.14
$3 off with signupwith signup
$ 202.92

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/21/2025

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About Symbyax

Symbyax is a brand-name combination prescription drug used to treat depressive episodes in bipolar disorder (manic-depressive illness) as well as severe depression that does not respond to other medications. Symbyax combines an SSRI, fluoxetine, which treats depression, with an antipsychotic, olanzapine, which treats psychosis and mania. On average, the retail price of Symbyax is $367.47, but only costs $75.03 with a SingleCare Symbyax coupon. Many local pharmacies—CVS, Target, Longs Drugs, Walgreens, and Duane Reade—accept SingleCare.

Symbyax Price History & Information

Price History for Symbyax (Brand) & Olanzapine-Fluoxetine Hcl (Generic)

30 count, capsule, 3-25mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Symbyax (Brand) & Olanzapine-Fluoxetine Hcl (Generic)

30 count, capsule, 3-25mg

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Symbyax

Symbyax is a brand-name combination prescription drug used to treat depressive episodes in bipolar disorder (manic-depressive illness) as well as severe depression that does not respond to other medications. Symbyax combines an SSRI, fluoxetine, which treats depression, with an antipsychotic, olanzapine, which treats psychosis and mania. On average, the retail price of Symbyax is $367.47, but only costs $75.03 with a SingleCare Symbyax coupon. Many local pharmacies—CVS, Target, Longs Drugs, Walgreens, and Duane Reade—accept SingleCare.

Symbyax FAQs

How much does Symbyax cost without insurance?

A prescription will cost around $367.47 for uninsured customers, but dosages may vary. With a SingleCare Symbyax coupon, you will pay only $75.03 per 30, 3-25mg capsules for the same prescription of Symbyax.

How much does Symbyax cost with insurance?

Your copay for Symbyax with insurance will vary depending on your plan and the dosage required. Ask your pharmacist to compare your insurance copay to SingleCare. You may find your SingleCare discount card saves you money—with SingleCare, Symbyax only costs $75.03.

Does Medicare cover Symbyax and how much does it cost?

Symbyax is usually not covered for Medicare-eligible patients under Medicare Part D and Medicare Advantage, but the generic, olanzapine-fluoxetine, is. Medicare patients can save money on a prescription for Symbyax with SingleCare Symbyax coupons—the price of Symbyax with a SingleCare discount card is only $75.03.

Is there a generic of Symbyax?

Symbyax is a brand-name prescription drug and several pharmaceutical companies manufacture generic Symbyax, including Par, Sandoz, and Teva. Before you pay for your Symbyax prescription, find free coupons for Symbyax or generic olanzapine-fluoxetine on our website or app.

What is Symbyax?

Symbyax is a brand-name combination prescription drug used to treat depressive episodes in bipolar disorder (manic-depressive illness) as well as severe depression that does not respond to other medications.

Fluoxetine belongs to a class of drugs called SSRIs (selective serotonin reuptake inhibitors). These drugs work by preventing chemicals important to nerve cell communication from being reabsorbed back into nerve cells. SSRIs, you might say, keep the communication channels between nerve cells open for a longer period of time. This strengthens circuits in the brain that are vital to regulating mood.

Olanzapine treats manic periods of bipolar disorder (manic-depressive illness) by blocking the brain activity that causes mania.

What are the side effects of Symbyax?

Although not a complete list, common side effects of Symbyax include diarrhea, weight gain, increased appetite, drowsiness, dizziness, decreased sex drive, insomnia, and shaking. Mental and mood changes can be severe and include confusion, nervousness, trouble concentrating, and restlessness. Allergic reactions to Symbyax are rare but include rashes, hives, and swelling. Severe skin reactions, such as Stevens-Johnson syndrome, are possible but very rare; these are marked by body-wide blistering and bleeding, fever, and liver damage.

Symbyax increases the amount of serotonin in the body. Too much serotonin (serotonin syndrome) can cause moderate to severe side effects, such as fever, agitation, overactive reflexes, dilated pupils, hallucinations, and sweating.

The most serious side effects are low sodium levels, high blood sugar, elevated risk for stroke or heart attack, and, most seriously, suicidal thoughts for patients under the age of 24. Prolonged use of Symbyax can result in a movement disorder that may not be reversible, characterized by involuntary muscle movements of the face, eyes, tongue, arms, and legs.

Symbyax is not an addictive drug, but may have withdrawal symptoms when discontinued abruptly.

Where are Symbyax coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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