Brand-name Phenergan has been discontinued in the United States. However, generic Phenergan, or promethazine, is available. Promethazine is a prescription drug that can help relieve allergy symptoms, nausea due to motion sickness, and pain and nausea after surgery. Promethazine is part of a class of drugs called phenothiazine derivatives that has antihistaminic, antiemetic, and sedative effects. Promethazine primarily blocks the actions of histamine to reduce symptoms of allergies and nausea. The retail price of promethazine tablets can be around $20.23 for 1, 1ml of 25mg/ml vial. A SingleCare Phenergan discount card may reduce the price of Phenergan to $26.83 for 1, 12 suppository box of generic Phenergan at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Brand-name Phenergan has been discontinued in the United States. However, generic Phenergan, or promethazine, is available. Promethazine is a prescription drug that can help relieve allergy symptoms, nausea due to motion sickness, and pain and nausea after surgery. Promethazine is part of a class of drugs called phenothiazine derivatives that has antihistaminic, antiemetic, and sedative effects. Promethazine primarily blocks the actions of histamine to reduce symptoms of allergies and nausea. The retail price of promethazine tablets can be around $20.23 for 1, 1ml of 25mg/ml vial. A SingleCare Phenergan discount card may reduce the price of Phenergan to $26.83 for 1, 12 suppository box of generic Phenergan at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Promethazine Hcl Retail Price | Promethazine Hcl SingleCare Price |
|---|---|---|
| CVS Pharmacy | $179.88 | $176.64 |
| Walmart | $26.64 | $25.08 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Brand-name Phenergan has been discontinued in the United States. However, generic Phenergan, or promethazine, is available. Promethazine is a prescription drug that can help relieve allergy symptoms, nausea due to motion sickness, and pain and nausea after surgery. Promethazine is part of a class of drugs called phenothiazine derivatives that has antihistaminic, antiemetic, and sedative effects. Promethazine primarily blocks the actions of histamine to reduce symptoms of allergies and nausea. The retail price of promethazine tablets can be around $20.23 for 1, 1ml of 25mg/ml vial. A SingleCare Phenergan discount card may reduce the price of Phenergan to $26.83 for 1, 12 suppository box of generic Phenergan at participating pharmacies.
You could pay an average cost of 1, 1ml of 25mg/ml vial for generic Phenergan without insurance. Instead, you may be able to pay a discount price of $26.83 for 1, 12 suppository box of generic Phenergan.
Generic Phenergan copay costs may vary depending on your insurance plan and the dosage prescribed. Consult with your insurance provider or pharmacist to determine your cost of promethazine with insurance. With SingleCare, our lowest price for generic Phenergan is $26.83 for 1, 12 suppository box of generic Phenergan. Ask your pharmacist to compare your savings options as a SingleCare card may save you more than your insurance.
Generic Phenergan is usually covered by Medicare prescription drug plans. For patients without Medicare or those without adequate Medicare coverage, a SingleCare card may be able to help reduce costs. With a SingleCare prescription discount card, the cash price of Phenergan could be only $26.83 for 1, 12 suppository box of generic Phenergan.
Phenergan is a brand-name prescription drug that is no longer available in pharmacies. Generic promethazine is available as a tablet, oral solution, rectal suppository, or injection.
Brand-name Phenergan has been discontinued in the United States. Generic Phenergan, or promethazine, is available in a number of formulations. Promethazine is a prescription drug that relieves allergy symptoms, such as itching. It can also be used to treat or prevent nausea due to motion sickness, as well as pain and nausea due to surgery. Generic Phenergan is sometimes used off-label as a sedative or sleep aid.
Promethazine, or generic Phenergan, is an antihistamine that works by blocking the actions of histamine. Histamine is a substance produced by the body that can cause symptoms of allergies and nausea from motion sickness or surgery.
Generic Phenergan is administered as a tablet, suppository, injection, or oral solution.
Side effects of Phenergan will depend on how Phenergan is administered and in what dose. In general, the side effects of Phenergan include, but are not limited to, drowsiness, dizziness, blurred vision, and dry mouth. Other side effects may include fatigue, ringing in the ears (tinnitus), confusion, nervousness, insomnia, and stuffy nose.
Serious side effects of Phenergan include respiratory depression and neuroleptic malignant syndrome, a life-threatening reaction to Phenergan. Neuroleptic malignant syndrome may cause symptoms like fever, confusion, changes in blood pressure, and fast heart rate.
Seek medical attention if you experience signs or symptoms of an allergic reaction, such as rash, swelling, or trouble breathing.
This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions. You can report any additional side effects to the FDA.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved