What is Mitigo? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 7, 2022

Mitigo overview

BRAND NAMES:

  • Duramorph, Infumorph 200, Infumorph 500, Mitigo

Generic Names:

  • Mitigo

Uses:

  • Treats moderate to severe pain. This medicine is a narcotic analgesic.

Therapeutic Classes:

  • Analgesic, Anesthetic Adjunct, Central Nervous System Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Mitigo used for?

What form(s) does Mitigo come in?

  • Injectable

What are common Mitigo dosages?

  • Vial 20ml of 200 mg/20ml(10 mg/ml)

Mitigo images - What does Mitigo look like?

  • Mitigo
    20ml of 200 mg/20ml(10 mg/ml) vial

How to take Mitigo

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine may be given through a needle (a shot) or a catheter (a small tube). It may be given under your skin, into a muscle, into a vein, or into your back.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • To avoid dizziness from this medicine, get up slowly from a sitting or lying position.

What to do if you miss a dose of Mitigo

  • You should not use two doses at the same time.

  • Use your medicine as soon as you remember that you have missed your dose.

  • If it is almost time for your next dose, wait until then to use your medicine and skip the missed dose.

Mitigo contraindications - Who shouldn't take Mitigo?

  • You should not use this medicine if you have ever had an allergic reaction to morphine or to related narcotic painkillers. You should not use morphine if you have asthma.

Mitigo warnings

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.

  • Before using this medicine, make sure your doctor knows if you have a seizure disorder (epilepsy), asthma, liver, heart, kidney, gallbladder, lung, or inflammatory bowel disease, a bleeding disorder, or an enlarged prostate.

  • This medicine may be habit-forming. You should not use more than your doctor ordered, or use it for longer periods of time than prescribed.

  • Talk to your doctor before you stop using this medicine. You may need to use smaller and smaller amounts before stopping completely.

  • This medicine may make you drowsy or dizzy. Avoid driving or using machinery.

  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Mitigo interactions & what to avoid when taking Mitigo

  • Make sure your doctor knows if you have taken an MAO inhibitor (Nardil®, Parnate®, Marplan®, Eldepryl®) within the last 14 days before using morphine.

  • Morphine may interact with many other drugs. Be sure your doctor knows of all other medicines you are taking.

  • Avoid drinking alcohol while using morphine.

  • Talk to your doctor before you stop using this medicine. You may need to use smaller and smaller amounts before stopping completely.

  • This medicine may make you drowsy or dizzy. Avoid driving or using machinery.

  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Mitigo side effects - How does Mitigo make you feel?

Serious Side Effects

  • Pain, burning, or swelling where the IV is given

  • Shortness of breath, trouble breathing

  • Skin rash, itching, or hives

  • Slow heartbeat

  • Trouble going to the bathroom (urinating)

  • Swelling in the legs, ankles, or feet

Less Serious Side Effects

  • Drowsiness, dizziness, or confusion

  • Constipation

  • Sweating

  • Nausea and vomiting