Mesna Coupons & Prices

Mesna FAQs

How much does Mesna cost without insurance?

Patients without insurance can expect to pay $56.44 for Mesna. With a SingleCare Mesna coupon, you will pay only $13.35 for the same injection if the hospital or clinic where you receive it accepts SingleCare.

How much does Mesna cost with insurance?

Your copay for Mesna with insurance will vary depending on your plan and the price charged for Mesna by the hospital or clinic for the injection. However, Mesna may be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic or hospital where you receive your Mesna injection if they will accept a SingleCare Mesna coupon; you could pay only $13.35.

Does Medicare cover Mesna and how much does it cost?

Mesna is sometimes covered for Medicare-eligible patients under Medicare prescription drug plans, but may also be covered under Medicare Part B as a medical benefit. Talk to your Medicare prescription drug insurance agent or representative to help you sort out your coverage for Mesna. Ask the clinic or hospital where you receive your Mesna injection if they will accept a SingleCare Mesna coupon; you could pay only $13.35.

Is there a generic of Mesna?

Mesna is a generic prescription drug and the active ingredient in Mesnex injections and tablets.

What is Mesna?

Mesna is a generic prescription drug used to prevent bleeding and swelling of the urinary bladder resulting treatment with ifosfamide (Ifex) or cyclophosphamide (Cytoxan), cancer chemotherapy drugs.

The body produces acrolein and nitric oxide when it metabolizes (breaks down) ifosfamide and cyclophosphamide. Acrolein concentrates in the bladder and kills the cells in the tissue lining the inside of the bladder, producing bleeding and sores along the inside of the bladder (hemorrhagic cystitis).

When the body metabolizes mesna, one of the substances produced attaches to acrolein and nitric oxide in the bladder and both are removed from the body in urine.

Mesna is administered as three injections or one injection and two Mesnex tablets on the day that cyclophosphamide or ifosfamide is administered. The first is given when the chemotherapy drug is administered, the second a few hours later, and the third a few hours after that.

What are the side effects of Mesna?

Most people will experience site reactions to the injection, such as pain, redness, or irritation. In general, the common side effects of Mesna include, but are not limited to, nausea, vomiting, constipation, low white blood cell counts, fatigue, fever, loss of appetite, low platelet levels, weakness, abdominal pain, hair loss, upset stomach, chest pain, and headache.

Serious side effects include low blood pressure, anemia, and low potassium.

Allergic reactions are rare, but can be severe and include anaphylaxis, a dangerous drop in blood pressure, and severe skin reactions. Tell your physician if you notice fever, sore throat, rash, swelling of the face or mouth, racing heartbeats, mouth sores, or trouble breathing.

This is not a complete list of possible side effects. Please be sure to consult with your prescribing physician about possible side effects of Mesna and any other concerns you may have.