What is Hydrocortisone-Acetic Acid? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

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Hydrocortisone-Acetic Acid overview

BRAND NAMES:

  • Acetasol HC, Oticot Hc

Generic Names:

  • Hydrocortisone-Acetic Acid

Uses:

  • Treats ear infections.

Therapeutic Classes:

  • Anti-Infective/Anti-Inflammatory Combination

Forms:

  • Liquid, Drop

How it’s taken:

  • Into the ear

What is Hydrocortisone-Acetic Acid used for?

Hydrocortisone-Acetic Acid contains an antibiotic (acetic acid) that treats infections caused by bacteria or fungus; and a steroid (hydrocortisone) that reduces the actions of chemicals in the body that cause inflammation. It works to treat symptoms associated with ear infections such as redness, itching, or swelling.

What form(s) does Hydrocortisone-Acetic Acid come in?

  • Liquid

  • Drop

What are common Hydrocortisone-Acetic Acid dosages?

  • Bottle 10ML of 1-2%

Hydrocortisone-Acetic Acid images - What does Hydrocortisone-Acetic Acid look like?

  • Hydrocortisone-Acetic Acid
    10ml of 1-2% bottle

How to take Hydrocortisone-Acetic Acid

  • Your doctor will tell you how much medicine to use and how often to use it.

  • Otic routeUse this medicine only in your ear.

  • Your doctor may insert a wick soaked with the medicine into your ear. Leave the wick in for as long as your doctor ordered. Add 3 to 5 drops of medicine to the wick every 4 to 6 hours. Your doctor may want you to continue to use the eardrops after you take the wick out.

  • Otic routeWash your hands with soap and water before and after using this medicine.

  • Otic routeLie down or tilt your head to the side. For a child, gently pull the child€™s earlobe down and back to straighten the child€™s ear canal. For an adult, gently pull the earlobe up and back to straighten the ear canal.

  • Otic routeDrop the prescribed number of drops into the ear. Keep the ear tilted up for a few minutes or put a cotton ball into your ear.

  • Otic routeRemove the cap. Do not let the tip of the dropper touch anything, including your ear.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Otic routeKeep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

  • Otic routeLie down or tilt your head to the side. For a child, gently pull the child€™s earlobe down and back to straighten the child€™s ear canal. For an adult, gently pull the earlobe up and back to straighten the ear canal.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Otic routeUse this medicine only in your ear.

  • Otic routeWash your hands with soap and water before and after using this medicine.

  • Your doctor will tell you how much medicine to use and how often to use it.

  • Otic routeRemove the cap. Do not let the tip of the dropper touch anything, including your ear.

  • Your doctor may insert a wick soaked with the medicine into your ear. Leave the wick in for as long as your doctor ordered. Add 3 to 5 drops of medicine to the wick every 4 to 6 hours. Your doctor may want you to continue to use the eardrops after you take the wick out.

  • Otic routeDrop the prescribed number of drops into the ear. Keep the ear tilted up for a few minutes or put a cotton ball into your ear.

  • Otic routeKeep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

What to do if you miss a dose of Hydrocortisone-Acetic Acid

Hydrocortisone-Acetic Acid contraindications - Who shouldn't take Hydrocortisone-Acetic Acid?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to acetic acid or hydrocortisone, or if you have vaccinia (cowpox), chickenpox, or a punctured eardrum.

Hydrocortisone-Acetic Acid warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you are pregnant or breastfeeding.

  • Call your doctor if your symptoms do not improve or if they get worse.

Hydrocortisone-Acetic Acid interactions & what to avoid when taking Hydrocortisone-Acetic Acid

  • Tell your doctor if you are pregnant or breastfeeding.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Hydrocortisone-Acetic Acid side effects - How does Hydrocortisone-Acetic Acid make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Ear pain, redness, or swelling that was not there before you used the medicine

Less Serious Side Effects

  • Burning, itching, dryness in the ear

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