Epivir Coupons & Prices

Lamivudine

Epivir is a brand-name prescription drug used in combination with other HIV drugs to reduce HIV virus, the infection that causes HIV/AIDS. The active ingredient in Epivir, lamivudine, blocks HIV from producing new virus particles. It is not a cure for HIV. The retail price for 30, 300mg tablets of Epivir is $559.38, but with a SingleCare Epivir coupon, the price is $45.84 for 30, 300mg tablets of generic Epivir. SingleCare Epivir coupons are accepted at many local pharmacies like Target, Walmart, Kroger, and Harris Teeter.

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Epivir coupon at CVS Pharmacy
$48.84
$ 45.84
$3 off with signupwith signup

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Epivir coupon at Food Lion Pharmacy
$ 59.00

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Epivir coupon at Kroger Pharmacy
$62.32
$ 59.32
$3 off with signupwith signup
Epivir coupon at Harris Teeter Pharmacy
$62.32
$ 59.32
$3 off with signupwith signup
Epivir coupon at Costco Pharmacy
$ 67.12
Epivir coupon at Walgreens Pharmacy
$71.74
$ 68.74
$3 off with signupwith signup
$ 225.03

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/21/2025

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About Epivir

Epivir is a brand-name prescription drug used in combination with other HIV drugs to reduce HIV virus, the infection that causes HIV/AIDS. The active ingredient in Epivir, lamivudine, blocks HIV from producing new virus particles. It is not a cure for HIV. The retail price for 30, 300mg tablets of Epivir is $559.38, but with a SingleCare Epivir coupon, the price is $45.84 for 30, 300mg tablets of generic Epivir. SingleCare Epivir coupons are accepted at many local pharmacies like Target, Walmart, Kroger, and Harris Teeter.

Epivir Price History & Information

Price History for Epivir (Brand) & Lamivudine (Generic)

30 count, tablet, 300mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Epivir

30 count, tablet, 300mg

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Epivir

Epivir is a brand-name prescription drug used in combination with other HIV drugs to reduce HIV virus, the infection that causes HIV/AIDS. The active ingredient in Epivir, lamivudine, blocks HIV from producing new virus particles. It is not a cure for HIV. The retail price for 30, 300mg tablets of Epivir is $559.38, but with a SingleCare Epivir coupon, the price is $45.84 for 30, 300mg tablets of generic Epivir. SingleCare Epivir coupons are accepted at many local pharmacies like Target, Walmart, Kroger, and Harris Teeter.

Epivir FAQs

How much does Epivir cost without insurance?

Uninsured customers pay an average of $559.38 for 30, 300mg tablets of Epivir. However, federal ADAP (AIDS Drug Assistance Program) will help uninsured HIV/AIDS patients with most or all of the Epivir cost, and the HarborPath ADAP Waiting List Program may help patients with Epivir during ADAP funding shortfalls. For uninsured patients on the ADAP waiting list who still cannot affordably fill their prescription, a SingleCare Epivir coupon reduces the cost to $45.84 per 30, 300mg tablets of generic Epivir.

How much does Epivir cost with insurance?

As an expensive prescription drug, Epivir copay costs may vary widely depending on your insurance plan and could be very high. With SingleCare, Epivir costs $45.84 per 30, 300mg tablets of generic Epivir, which may be lower than your copay with your insurance company. So ask your local pharmacist to compare your insurance copay to the SingleCare discount card.

Does Medicare cover Epivir and how much does it cost?

Brand-name Epivir is usually not covered by Medicare prescription drug plans, but the generic, lamivudine, is. Patients without coverage can turn to ADAP for assistance. For those on the ADAP waiting list who still cannot affordably fill their prescription, a SingleCare Epivir coupon reduces the cost of a generic Epivir prescription to $45.84 for 30, 300mg tablets.

Is there a generic of Epivir?

The active ingredient in Epivir is lamivudine and it is available as a generic prescription drug from Aurobindo, Mylan, Lupin, and other generic manufacturers.

What is Epivir?

Epivir is a brand-name prescription drug that targets HIV, the virus that causes HIV/AIDS. HIV is a retrovirus, so the active ingredient in Epivir, lamivudine, belongs to a class called antiretroviral drugs because it prevents the retrovirus from producing new virus particles.

Because the HIV virus is constantly mutating and creating new strains, Epivir is always used in combination with other antiretroviral drugs for maximum effectiveness.

The HIV virus attacks a particular type of white blood cell that is critical in the body's ability to fight off infections and cancers. As a result, patients infected with HIV can suffer from opportunistic infections and cancers that become increasingly life-threatening as the immune system deteriorates. Reducing the amount of HIV virus in the body helps the body's immune system to recover so that it can successfully fight off these illnesses.

Epivir is taken as a tablet or oral solution once or twice daily. 

There are two forms of Epivir. Epivir is used for HIV and Epivir HBV is used to treat hepatitis B. These drugs are not interchangeable. Epivir contains a higher dose of lamivudine than Epivir HBV. If you have both HIV and hepatitis, you should only take Epivir. If you have ever had hepatitis B, it may become active or worsen after you stop taking Epivir. Your healthcare provider will order regular liver function tests. 

Epivir is not a cure, and taking this medication will not prevent the disease from spreading. Do not have unprotected sex. Do not share personal items such as medicine needles, razors, or toothbrushes. Consult your provider regarding safe ways to prevent spreading HIV during sex. 

Refill your prescription several days before you need it, so that you never run out of medicine.

What are the side effects of Epivir?

The most common side effects of Epivir are cough, runny nose, headache, diarrhea, nausea, vomiting, “feeling bad” (malaise), problems sleeping, tired feeling, muscle and joint pain, appetite loss, dizziness, depression, and numbness and tingling. Severe reactions may include pancreas problems or liver problems. Call your doctor right away if you have severe upper stomach pain that spreads to the back, nausea, appetite loss, dark urine, or yellowing of the skin or whites of the eyes. A potentially severe buildup of lactic acid in the body (lactic acidosis) can occur. Symptoms can start out mild, but progress quickly, and the condition can cause death. Get emergency medical help if you have muscle pain, difficulty breathing, stomach pain, vomiting, irregular heart rate, dizziness, or if you feel cold, weak, or tired.

Allergic reactions are rare, but discontinue Epivir and get emergency medical help if any allergic symptoms, such as rash, swelling, or trouble breathing, are experienced. This is not a complete list of side effects. Your physician will address your questions and concerns regarding potential side effects.

Where are Epivir coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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