Epivir is a brand-name prescription drug used in combination with other HIV drugs to reduce HIV virus, the infection that causes HIV/AIDS. The active ingredient in Epivir, lamivudine, blocks HIV from producing new virus particles. It is not a cure for HIV. The retail price for 30, 300mg tablets of Epivir is $559.38, but with a SingleCare Epivir coupon, the price is $45.84 for 30, 300mg tablets of generic Epivir. SingleCare Epivir coupons are accepted at many local pharmacies like Target, Walmart, Kroger, and Harris Teeter.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/21/2025
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Epivir is a brand-name prescription drug used in combination with other HIV drugs to reduce HIV virus, the infection that causes HIV/AIDS. The active ingredient in Epivir, lamivudine, blocks HIV from producing new virus particles. It is not a cure for HIV. The retail price for 30, 300mg tablets of Epivir is $559.38, but with a SingleCare Epivir coupon, the price is $45.84 for 30, 300mg tablets of generic Epivir. SingleCare Epivir coupons are accepted at many local pharmacies like Target, Walmart, Kroger, and Harris Teeter.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Epivir is a brand-name prescription drug used in combination with other HIV drugs to reduce HIV virus, the infection that causes HIV/AIDS. The active ingredient in Epivir, lamivudine, blocks HIV from producing new virus particles. It is not a cure for HIV. The retail price for 30, 300mg tablets of Epivir is $559.38, but with a SingleCare Epivir coupon, the price is $45.84 for 30, 300mg tablets of generic Epivir. SingleCare Epivir coupons are accepted at many local pharmacies like Target, Walmart, Kroger, and Harris Teeter.
Uninsured customers pay an average of $559.38 for 30, 300mg tablets of Epivir. However, federal ADAP (AIDS Drug Assistance Program) will help uninsured HIV/AIDS patients with most or all of the Epivir cost, and the HarborPath ADAP Waiting List Program may help patients with Epivir during ADAP funding shortfalls. For uninsured patients on the ADAP waiting list who still cannot affordably fill their prescription, a SingleCare Epivir coupon reduces the cost to $45.84 per 30, 300mg tablets of generic Epivir.
As an expensive prescription drug, Epivir copay costs may vary widely depending on your insurance plan and could be very high. With SingleCare, Epivir costs $45.84 per 30, 300mg tablets of generic Epivir, which may be lower than your copay with your insurance company. So ask your local pharmacist to compare your insurance copay to the SingleCare discount card.
Brand-name Epivir is usually not covered by Medicare prescription drug plans, but the generic, lamivudine, is. Patients without coverage can turn to ADAP for assistance. For those on the ADAP waiting list who still cannot affordably fill their prescription, a SingleCare Epivir coupon reduces the cost of a generic Epivir prescription to $45.84 for 30, 300mg tablets.
The active ingredient in Epivir is lamivudine and it is available as a generic prescription drug from Aurobindo, Mylan, Lupin, and other generic manufacturers.
Epivir is a brand-name prescription drug that targets HIV, the virus that causes HIV/AIDS. HIV is a retrovirus, so the active ingredient in Epivir, lamivudine, belongs to a class called antiretroviral drugs because it prevents the retrovirus from producing new virus particles.
Because the HIV virus is constantly mutating and creating new strains, Epivir is always used in combination with other antiretroviral drugs for maximum effectiveness.
The HIV virus attacks a particular type of white blood cell that is critical in the body's ability to fight off infections and cancers. As a result, patients infected with HIV can suffer from opportunistic infections and cancers that become increasingly life-threatening as the immune system deteriorates. Reducing the amount of HIV virus in the body helps the body's immune system to recover so that it can successfully fight off these illnesses.
Epivir is taken as a tablet or oral solution once or twice daily.
There are two forms of Epivir. Epivir is used for HIV and Epivir HBV is used to treat hepatitis B. These drugs are not interchangeable. Epivir contains a higher dose of lamivudine than Epivir HBV. If you have both HIV and hepatitis, you should only take Epivir. If you have ever had hepatitis B, it may become active or worsen after you stop taking Epivir. Your healthcare provider will order regular liver function tests.
Epivir is not a cure, and taking this medication will not prevent the disease from spreading. Do not have unprotected sex. Do not share personal items such as medicine needles, razors, or toothbrushes. Consult your provider regarding safe ways to prevent spreading HIV during sex.
Refill your prescription several days before you need it, so that you never run out of medicine.
The most common side effects of Epivir are cough, runny nose, headache, diarrhea, nausea, vomiting, “feeling bad” (malaise), problems sleeping, tired feeling, muscle and joint pain, appetite loss, dizziness, depression, and numbness and tingling. Severe reactions may include pancreas problems or liver problems. Call your doctor right away if you have severe upper stomach pain that spreads to the back, nausea, appetite loss, dark urine, or yellowing of the skin or whites of the eyes. A potentially severe buildup of lactic acid in the body (lactic acidosis) can occur. Symptoms can start out mild, but progress quickly, and the condition can cause death. Get emergency medical help if you have muscle pain, difficulty breathing, stomach pain, vomiting, irregular heart rate, dizziness, or if you feel cold, weak, or tired.
Allergic reactions are rare, but discontinue Epivir and get emergency medical help if any allergic symptoms, such as rash, swelling, or trouble breathing, are experienced. This is not a complete list of side effects. Your physician will address your questions and concerns regarding potential side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved