What is Bupivacaine in Dextrose? Uses, warnings & side effects

Updated May 14, 2025  •  Published Sep 24, 2021

Bupivacaine in Dextrose overview

BRAND NAMES:

  • Bupivacaine HCl Novaplus, Bupivacaine Spinal, Marcaine, Marcaine HCl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF, Active Injection Kit LM-Dep-2, Active Injection Kit M-1, BL Injection Kit, BT Injection Kit, Bupivilog Kit

Generic Names:

  • Bupivacaine In Dextrose

Uses:

  • Numbs an area of your body during or after surgery or other procedures, including childbirth, shoulder surgery, or dental work. This medicine is a local anesthetic.

Therapeutic Classes:

  • Anesthetic, Local

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Bupivacaine in Dextrose used for?

What form(s) does Bupivacaine in Dextrose come in?

  • Injectable

What are common Bupivacaine in Dextrose dosages?

  • Ampule 2ML of 0.75-8.25%

Bupivacaine in Dextrose images - What does Bupivacaine in Dextrose look like?

  • BUPivacaine in Dextrose
    2ml of 0.75-8.25% ampule

How to take Bupivacaine in Dextrose

  • A nurse or other trained health professional will give you this medicine in a medical facility. Marcaine„¢ is sometimes given through a catheter placed into your lower back for an epidural or a spinal block. You may also receive the injection into your rib cage, chest, or other body areas. This medicine may also be injected directly into your gums for dental work. Posimir® is usually given in the shoulder area.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Bupivacaine in Dextrose

Bupivacaine in Dextrose contraindications - Who shouldn't take Bupivacaine in Dextrose?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to bupivacaine or similar medicines, or if you have severe bleeding, low blood pressure, any type of infection, heart rhythm problems, or an infection at the injection site. Posimir® should not be used to ease labor pains during childbirth.

Bupivacaine in Dextrose warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, blood or blood clotting problems (including methemoglobinemia), asthma, diabetes, seizures, myasthenia gravis, thyroid problems, high blood pressure, low blood pressure, lasting back pain, arthritis, spinal problems, lung or breathing problems, G6PD, or mental illness.

  • This medicine may cause the following problems:Methemoglobinemia (blood disorder)Chondrolysis (a bone or joint problem)Low blood pressureHyperthermia (a dangerous increase in body temperature)

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine should cause numbness only to the area where it is injected. It is not meant to cause you to fall asleep or become unconscious.

  • You may experience temporary loss of sensation and movement, usually in the lower half of your body, if you receive this medicine into your lower back (epidural).

  • If you are receiving this medicine as an epidural to ease labor pains, it may take longer than normal for you to push your baby out. It is also possible that the baby may have unwanted effects after birth (including sleepiness, slow responses). Talk to your doctor if you have questions about how this medicine might affect your baby.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Bupivacaine in Dextrose interactions & what to avoid when taking Bupivacaine in Dextrose

  • Some medicines can affect how bupivacaine works. Tell your doctor if you are taking any of the following: Acetaminophen, chloroquine, metoclopramide, primaquine, quinine, sulfasalazineBlood pressure medicine (including atenolol, doxazosin, lisinopril, metoprolol, terazosin)Cancer medicine (including cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase)Ergot medicine or other medicines for headaches or migrainesMedicine to treat depression (including an MAO inhibitor, tricyclic antidepressant)Medicine to treat an infection (including dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides)Medicine to treat seizures (including phenobarbital, phenytoin, sodium valproate)Nitrate or nitrite medicine (including nitric oxide, nitroglycerin, nitroprusside, nitrous oxide)Other local anestheticsPhenothiazine medicine (including chlorpromazine, promethazine)

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • This medicine should cause numbness only to the area where it is injected. It is not meant to cause you to fall asleep or become unconscious.

  • It may be easier to hurt yourself while your treated body area is still numb. Be careful to avoid injury until you have regained all the feeling and are no longer numb.

  • If you are receiving this medicine as an epidural to ease labor pains, it may take longer than normal for you to push your baby out. It is also possible that the baby may have unwanted effects after birth (sleepiness, slow responses). Talk to your doctor if you have questions about how this medicine might affect your baby.

Bupivacaine in Dextrose side effects - How does Bupivacaine in Dextrose make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Anxiety, depression, restlessness, drowsiness, ringing in your ears, blurred vision

  • Bone or joint pain or stiffness, inability to move

  • Change in how much or how often you urinate, difficult or painful urination

  • Chest pain, fast, pounding, slow, or uneven heartbeat, trouble breathing

  • Dry mouth, increased thirst, muscle cramps

  • Fever, chills, cough, sore throat, body aches

  • Lightheadedness, dizziness, or fainting

  • Nausea, vomiting, metallic taste in your mouth or other changes in taste

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Pale, gray, or blue lips, nails, or skin, dark urine, headache, tiredness

  • Seizures, shivering, shaking, or tremors

  • Unusual bleeding, bruising, or weakness

Less Serious Side Effects

  • Back pain

  • Constipation, diarrhea, stomach pain or upset

  • Pain, redness, or swelling where the needle was placed

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