What is Brevital Sodium? Uses, warnings & side effects

Updated May 14, 2025  •  Published Feb 14, 2024

Brevital Sodium overview

BRAND NAMES:

  • Brevital Sodium

Generic Names:

  • Brevital Sodium

Uses:

  • Causes you to fall asleep during a surgery or medical procedure. This medicine is an anesthetic.

Therapeutic Classes:

  • Anesthetic Adjunct

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Brevital Sodium used for?

What form(s) does Brevital Sodium come in?

  • Injectable

What are common Brevital Sodium dosages?

  • Solution Reconstituted 500mg

Brevital Sodium images - What does Brevital Sodium look like?

  • Brevital Sodium
    500mg solution reconstituted

How to take Brevital Sodium

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Brevital Sodium

Brevital Sodium contraindications - Who shouldn't take Brevital Sodium?

  • You should not use this medicine if you have had an allergic reaction to methohexital, or barbiturates, or if you have porphyria.

Brevital Sodium warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding.

  • Make sure your doctor knows if you have heart disease, lung disease, liver disease, kidney disease, asthma, seizures (epilepsy), high or low blood pressure, or severe anemia.

  • This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Pain in your lower leg (calf).

  • Tremors or seizures.

Brevital Sodium interactions & what to avoid when taking Brevital Sodium

  • Make sure your doctor knows if you are using medicines for seizures such as phenytoin (Dilantin®), or blood thinners such as warfarin (Coumadin®). Tell your doctor if you are also using steroid medicine such as dexamethasone, prednisolone, prednisone, or Medrol®. Make sure your doctor knows if you are also using products that contain ethyl alcohol or propylene glycol.

  • Make sure your doctor knows if you have heart disease, lung disease, liver disease, kidney disease, asthma, seizures (epilepsy), high or low blood pressure, or severe anemia.

  • This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Brevital Sodium side effects - How does Brevital Sodium make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fast heartbeat.

  • Lightheadedness or fainting

  • Numbness or weakness in your arm, leg, or on one side of your body.

  • Pain in your lower leg (calf).

  • Tremors or seizures.

Less Serious Side Effects

  • Headache.

  • Nervousness, restlessness, anxiety, or agitation.

  • Confusion, drowsiness, weakness, or muscle twitching.

  • Mild skin rash, or itching.

  • Mild nausea, vomiting, or stomach pain.

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.