What is Bendeka? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 31, 2020

Bendeka overview

BRAND NAMES:

  • Treanda, Belrapzo, Bendeka

Generic Names:

  • Bendeka

Uses:

  • Treats chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Bendeka used for?

Bendeka is a cancer medicine that comes in the form of an intravenous solution. It is used to treat chronic lymphocytic leukemia. It works by interfering with the spread and growth of cancer cells in the body. This medicine is also used to treat indolent B-cell non-Hodgkin lymphoma after other medicines have been tried unsuccessfully to treat this condition. Do not use Bendeka if you are pregnant as it could harm the unborn baby. Common side effects may include fever, cough, mouth sores, trouble breathing and nausea.

What form(s) does Bendeka come in?

  • Injectable

What are common Bendeka dosages?

  • Vial 4ML of 100MG/4ML

Bendeka images - What does Bendeka look like?

  • Bendeka
    4ml of 100mg/4ml vial

How to take Bendeka

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

What to do if you miss a dose of Bendeka

Bendeka contraindications - Who shouldn't take Bendeka?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to bendamustine, polyethylene glycol 400, propylene glycol, or monothioglycerol, or if you are pregnant.

Bendeka warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Injection routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Women should continue to use birth control for 6 months and for men 3 months after treatment ends.

  • Tell your doctor if you have kidney disease, liver disease, cancer, or any kind of infection.

  • Do not breastfeed during treatment and for at least 1 week after the last dose.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may cause the following problems:Tumor lysis syndrome (electrolyte and metabolic problems that can be life-threatening)Serious skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS)Liver problems

  • This medicine may make you feel weak or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

Bendeka interactions & what to avoid when taking Bendeka

  • Some medicines can affect how bendamustine works. Tell your doctor if you are using ciprofloxacin, fluvoxamine, or omeprazole.

  • Do not smoke while you are using this medicine.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may cause the following problems:Tumor lysis syndrome (electrolyte and metabolic problems that can be life-threatening)Serious skin reactions

  • This medicine may make you feel weak or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Bendeka side effects - How does Bendeka make you feel?

Serious Side Effects

  • Pain, redness, swelling, or a lump under your skin where the needle is placed

  • Change in how much or how often you urinate, lower back or side pain

  • Unusual bleeding, bruising, or weakness

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Fever, chills, cough, sore throat, body aches

Less Serious Side Effects

  • Diarrhea, constipation

  • Tiredness, headache

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