What is Allergy Relief-D? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Allergy Relief-D overview

BRAND NAMES:

  • Alahist D, Acticon, Acta-Tabs PE, Aprodine, Allergy Relief Nasal Decongestant, Antihistamine & Nasal Decongestant, Allergy Plus Sinus, Allergy Relief-D, Allergy & Congestion Relief, Allegra-D 24HR, Allegra-D 24 Hour Allergy & Congestion, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 12 Hour, Allegra-D, Ala-Hist PE, Loratadine D, Leader Allergy Relief D-24, Alavert D-12 Hour, Allergy & Congestion Relief, Allergy Relief, Allergy Relief-D, Claritin-D, Claritin-D 12HR, Claritin-D 24 Hour, Good Neighbor Allergy & Congestion Relief 24 Hour, Good Neighbor Pharmacy Allergy & Congestion Relief, Good Neighbor Pharmacy Loratadine-D, Health Mart Allergy Relief & Nasal Decongestant, Kirkland Signature AllerClear-D, Leader Allergy Relief D-12, Allegra-D, Allegra-D 12 Hour, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 24 Hour Allergy & Congestion, Allegra-D 24HR, Allergy Relief-D, Antihistamine & Nasal Decongestant, Leader 12HR Allergy and Congestion, Wal-Fex D

Generic Names:

  • Allergy Relief-D

Uses:

  • Treats stuffy nose, sneezing, runny nose, and sinus congestion caused by hay fever, colds, or flu., Treats allergy (hay fever) symptoms such as sneezing, runny or stuffy nose, itchy throat, and itchy or watery eyes. This medicine is a combination of an antihistamine and a decongestant., Treats hay fever symptoms such as a runny or stuffy nose, sneezing, and watery eyes. Loratadine is an antihistamine, and pseudoephedrine is a decongestant.

Therapeutic Classes:

  • Antihistamine, Less-Sedating/Decongestant Combination, Antihistamine/Antitussive Combination, Antihistamine/Decongestant Combination, Respiratory Agent, Antihistamine, Less-Sedating/Decongestant Combination, Antihistamine/Decongestant Combination, Antihistamine, Less-Sedating/Decongestant Combination, Antihistamine/Decongestant Combination

Forms:

  • Thin Sheet, Capsule, Long Acting Capsule, Tablet, Long Acting Tablet, Chewable Tablet, 24 Hour Tablet, Dissolving Tablet, Liquid, Drop, Long Acting Tablet, 24 Hour Tablet, 12 Hour Tablet, Long Acting Tablet, 24 Hour Tablet

How it’s taken:

  • By mouth, By mouth, By mouth

What is Allergy Relief-D used for?

What form(s) does Allergy Relief-D come in?

  • Thin Sheet

  • Capsule

  • Long Acting Capsule

  • Tablet

  • Long Acting Tablet

  • Chewable Tablet

  • 24 Hour Tablet

  • Dissolving Tablet

  • Liquid

  • Drop

  • Long Acting Tablet

  • 24 Hour Tablet

  • 12 Hour Tablet

  • Long Acting Tablet

  • 24 Hour Tablet

What are common Allergy Relief-D dosages?

  • Tablet Extended Release 24 Hour 10-240MG

Allergy Relief-D images - What does Allergy Relief-D look like?

  • Allergy Relief-D
    10-240mg tablet extended release 24 hour

How to take Allergy Relief-D

  • Your doctor will tell you how much to take and how often. You should not use more of this medicine than your doctor ordered.

  • Claritin-D 24 Hour® extended-release tablets should only be taken once a day.

  • Take the tablet with a full glass of water.

  • Swallow the tablet whole. Do not break, crush, or chew.

  • It is best to take this medicine on an empty stomach.

  • Drink plenty of liquids while taking this medicine.

  • It is best to take this medicine on an empty stomach.

  • Swallow the tablet whole. Do not break, crush, or chew.

  • Drink plenty of liquids while taking this medicine.

  • Your doctor will tell you how much to take and how often. You should not use more of this medicine than your doctor ordered.

  • Claritin-D 24 Hour® extended-release tablets should only be taken once a day.

  • Take the tablet with a full glass of water.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Swallow the tablet whole. Do not crush, chew, or break the tablet.

  • Oral routeIt is best to take this medicine on an empty stomach.

  • This medicine is not for children under 12 years of age.

  • This medicine is not for children under 12 years of age.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral routeIt is best to take this medicine on an empty stomach.

  • Swallow the tablet whole. Do not crush, chew, or break the tablet.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Completely chew the chewable tablet before swallowing it. Swallow the regular tablet, regular capsule, extended-release tablet, or extended-release capsule whole. Do not crush, break, or chew it.

  • If you use a powder, stir the medicine into water and drink it right away. Do not keep any unused mixture to take later.

  • If you are using the Softchew®, you may let it melt in your mouth, or you may chew it. If you are using the dissolving tablet, let the tablet melt in your mouth.

  • Measure the oral liquid medicine with a marked measuring spoon, medicine cup, oral syringe, or medicine dropper.

  • You might need to shake the oral liquid well just before you use it. Follow the directions on the label or ask your pharmacist.

  • Measure the oral liquid medicine with a marked measuring spoon, medicine cup, oral syringe, or medicine dropper.

  • Completely chew the chewable tablet before swallowing it. Swallow the regular tablet, regular capsule, extended-release tablet, or extended-release capsule whole. Do not crush, break, or chew it.

  • If you use a powder, stir the medicine into water and drink it right away. Do not keep any unused mixture to take later.

  • You might need to shake the oral liquid well just before you use it. Follow the directions on the label or ask your pharmacist.

  • If you are using the Softchew®, you may let it melt in your mouth, or you may chew it. If you are using the dissolving tablet, let the tablet melt in your mouth.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

What to do if you miss a dose of Allergy Relief-D

  • If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.

  • Do not use extra medicine to make up for a missed dose.

  • Keep all medicine away from children and never share your medicine with anyone.

  • If you miss a dose or forget to use your medicine, use it as soon as you can. Then wait at least 12 hours before taking your next dose. Do not use two doses at the same time.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • You should not use two doses at the same time.

  • Skip the missed dose if it is almost time for your next regular dose.

  • Take your medicine as soon as possible unless it is almost time for your next dose. If you are taking Claritin-D 24 Hour®, you should only take one dose a day.

Allergy Relief-D contraindications - Who shouldn't take Allergy Relief-D?

  • You should not use this medicine if you have had an allergic reaction to loratadine or pseudoephedrine. If you have glaucoma, problems urinating, severe high blood pressure, or heart disease or if you have taken a type of medicine called an MAO inhibitor (such as Marplan®, Parnate®, or Nardil®) in the past 14 days, then you should not take this medicine. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years old. Using these medicines in very young children might cause serious or possibly life-threatening side effects.

  • You should not use this medicine if you have had an allergic reaction to fexofenadine or pseudoephedrine. Tell your doctor if you have ever had an allergic reaction to any drug. You should not use this medicine if you have narrow-angle glaucoma, severe hypertension, or severe heart disease, or if you are unable to urinate. You should not use this medicine if you have used an MAO inhibitor such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

  • You should not use this medicine if you have had an allergic reaction to any antihistamine or decongestant, or if you have used an MAO inhibitor (such as Nardil®, Marplan®, or Parnate®) within the past 14 days. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years old. Using these medicines in very young children might cause serious or possibly life-threatening side effects.

Allergy Relief-D warnings

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.

  • Make sure your doctor knows if you have liver disease, diabetes, thyroid problems, high blood pressure, kidney disease, or prostate problems before taking this medicine.

  • You should not use Claritin-D 24 Hour® tablets if you have trouble swallowing tablets. The tablet could get stuck as it passes down toward your stomach.

  • This medicine may make you drowsy or dizzy. Be careful if you are driving or using machinery.

  • Make sure your doctor knows if you are pregnant or breast feeding.

  • Tell your doctor if you have diabetes, glaucoma, heart disease, high blood pressure, or an overactive thyroid. Make sure your doctor knows if you have kidney disease, or trouble urinating due to an enlarged prostate.

  • Decrease in how much or how often you urinate.

  • Fast, irregular, or pounding heartbeat.

  • Hallucinations.

  • Lightheadedness, fainting, or convulsions (seizures).

  • Problems with urination.

  • Severe weakness, dizziness, tremors, or trouble sleeping.

  • Some brands of this medicine may contain alcohol. Read the label carefully or ask your pharmacist so you know what is in your product.

  • Children may be more sensitive to this medicine than adults, especially if they take too much. Always read the medicine label closely so you give your child the right amount. Ask your pharmacist or doctor if you are not sure how much medicine to give your child.

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, high blood pressure, diabetes, liver disease, glaucoma, asthma, emphysema, seizure disorder, a disorder of the urinary tract, or an overactive thyroid.

  • If your symptoms do not improve within 7 days or if they get worse, call your doctor. If you have a severe sore throat, fever, or thick yellow or green mucus, call your doctor.

  • Some brands of this medicine may contain phenylalanine (aspartame). If you have a health problem called phenylketonuria, ask your doctor before using this medicine.

  • This medicine can make you drowsy or restless. Avoid taking at bedtime if it makes you restless. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Allergy Relief-D interactions & what to avoid when taking Allergy Relief-D

  • Avoid drinking alcohol or using any other medicines that make you sleepy. These include sleeping pills, other cold and allergy medicine, narcotic pain relievers, and sedatives.

  • If your symptoms do not improve within 7 days or if they get worse, call your doctor. If you have a severe sore throat, fever, or thick yellow or green mucus, call your doctor.

  • Some brands of this medicine may contain phenylalanine (aspartame). If you have a health problem called phenylketonuria, ask your doctor before using this medicine.

  • This medicine can make you drowsy or restless. Avoid taking at bedtime if it makes you restless. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • Some brands of this medicine may contain alcohol. Read the label carefully or ask your pharmacist so you know what is in your product.

  • Children may be more sensitive to this medicine than adults, especially if they take too much. Always read the medicine label closely so you give your child the right amount. Ask your pharmacist or doctor if you are not sure how much medicine to give your child.

  • Avoid drinking fruit juices such as apple juice, orange juice, and grapefruit juice while you are using this medicine.

  • Make sure your doctor knows about all other medicines you are using, especially erythromycin (E-Mycin®, E.E.S.®), digoxin (Lanoxin®), ketoconazole (Nizoral®), or medicine for high blood pressure.

  • Tell your doctor if you are using an antacid such as Maalox®. Certain antacids should not be taken together with fexofenadine/pseudoephedrine. Ask your doctor about how much time to allow between taking this medicine and taking an antacid.

  • Do not use any other allergy or cold medicines with fexofenadine/pseudoephedrine unless your doctor tells you to.

  • Avoid drinking alcohol while taking this medicine.

  • You should not use other antihistamines or decongestants while taking this medicine, including those you buy without a doctor's prescription.

  • Make sure your doctor knows if you are also taking medicine for high blood pressure, ketoconazole (Nizoral®), cimetidine (Tagamet®), or erythromycin (E.E.S.®, ERYC®, Ery-Tab®, and others).

  • This medicine may make you drowsy or dizzy. Be careful if you are driving or using machinery.

Allergy Relief-D side effects - How does Allergy Relief-D make you feel?

Serious Side Effects

  • Trouble breathing

  • Fast, pounding, or irregular heartbeat

  • Severe headache

  • Skin rash, hives, or itching

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Cough, sneezing, sore throat, chest congestion.

  • Decrease in how much or how often you urinate.

  • Fast, irregular, or pounding heartbeat.

  • Hallucinations.

  • Lightheadedness, fainting, or convulsions (seizures).

  • Severe weakness, dizziness, tremors, or trouble sleeping.

  • Problems with urination.

  • Dizziness or drowsiness

  • Fainting or passing out

  • Dry mouth or nose

  • Wheezing or trouble breathing

  • Fast, pounding, or irregular heartbeat

Less Serious Side Effects

  • Headache

  • Dizziness or drowsiness

  • Dry mouth or nose

  • Trouble sleeping

  • Nervousness

  • Dry mouth, irritated throat.

  • Sweating or increased thirst.

  • Headache, drowsiness.

  • Feeling restless, anxious, fearful, or excited.

  • Nausea or upset stomach.

  • Dry mouth, nose, or throat

  • Trouble urinating

  • Nausea

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