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How much is Vyzulta without insurance?

Vyzulta costs $320 without insurance. Learn how to get Vyzulta at a lower price or find cheaper alternatives.
Rx eye drops: Vyzulta without insurance

Key takeaways

  • Vyzulta, a prescription eye drop for reducing eye pressure in glaucoma patients, costs about $320 for a 2.5 mL bottle without insurance.

  • There is no generic version of Vyzulta available until possibly 2025, but cheaper generic alternatives for other prostaglandin analogs exist.

  • Insurance coverage for Vyzulta varies, with many plans not covering it due to available alternatives, potentially leading to high copays for those that do.

  • You can save on Vyzulta with patient assistance programs, manufacturer coupons, and a SingleCare prescription discount card, which can lower the price to $245.

Vyzulta is a brand-name prescription eye drop medication that is approved by the Food and Drug Administration (FDA) to reduce eye pressure in people with open-angle glaucoma or high eye pressure. When intraocular pressure gets too high, it can damage the retina, causing glaucoma and blindness. The active ingredient in Vyzulta, latanoprostene bunod, is a prostaglandin analog that promotes fluid drainage from the inside of the eye, decreasing eye pressure. Vyzulta is usually prescribed to instill one drop in the affected eye or eyes each day. Common side effects of Vyzulta include eye irritation, eye pain, and eyelash growth. As a brand-name prescription drug, Vyzulta is premium-priced, but there are ways to save money.

What is the generic for Vyzulta?

At this time, there is no generic version of Vyzulta ophthalmic solution. The earliest date that a generic version could be available is in 2025.

Is Vyzulta covered by insurance?

Some commercial insurance plans and Medicare drug plans provide coverage for a Vyzulta prescription. However, many don’t because of the number of alternative drugs similar to Vyzulta. When covered, Vyzulta may have a high copay cost.

How much does Vyzulta cost without insurance?

Vyzulta is a brand-name drug that costs more than generic prostaglandin analogs. A 2.5 mL eye dropper bottle costs about $320 at the average retail price. A 2.5 mL bottle contains 50 drops. A 2.5 mL bottle should last about a month if both eyes are being treated. At that rate, the yearly cost of Vyzulta treatment works out to almost $4,000.

Fortunately, there are generic alternatives. Prostaglandin analogs that work similarly to Vyzulta include latanoprost ($80 for a 2.5 mL bottle), bimatoprost ($186 for 3 mL), and travoprost ($223 for 2.5 mL). All of these drugs work the same way as Vyzulta. However, these drugs have likely been tried before Vyzulta was prescribed. If not, ask the prescribing healthcare provider for medical advice about less costly alternatives.

Other types of drugs can also be used, including alpha-adrenergics (brimonidine), beta blockers (timolol), and carbonic anhydrase inhibitors (dorzolamide). Keep in mind that these other drugs differ in the effectiveness and side effects of Vyzulta. 

People prescribed Vyzulta may also have to take one or more of these other eye drop medications. In that case, it may be cheaper to take a combination drug rather than take each one separately. If given multiple prescriptions for intraocular pressure (IOP) or glaucoma, ask the ophthalmologist about combination drugs to save money.

The best way to save money may not be to explore alternative drugs but to use a SingleCare prescription discount card. With SingleCare, the lowest discount price for Vyzulta is only $245 for a 2.5 mL bottle.

Drug name Price without insurance of brand-name drug  SingleCare price Savings options
Vyzulta $320 per 2.5 mL bottle of 0.024% solution $245 per 2.5 mL bottle of 0.024% solution of brand-name Vyzulta See latest prices
Latanoprost $83 per 2.5 mL bottle of 0.005% solution $10 per 2.5 mL bottle of 0.005% solution of generic latanoprost See latest prices
Rocklatan

(netarsudil/ latanoprost)

$434 per 2.5 mL bottle of 0.02-0.005% solution $330 per 2.5 mL bottle of 0.02-0.005% solution of brand-name Rocklatan See latest prices
Rhopressa

(netarsudil dimesylate)

$383 per 2.5 mL bottle of 0.02% solution  $313 per 2.5 mL bottle of 0.02% solution of brand-name Rhopressa See latest prices
Alphagan P

(brimonidine tartrate)

$249 per 5 mL bottle of 0.155% solution $35 per 5 mL bottle of 0.155% solution of generic Alphagan P See latest prices
Cosopt

(dorzolamide HCl-timolol mal)

$262 per 10 mL bottle of 22.3-6.8 mg/mL solution $15 per 10 mL bottle of 22.3-6.8 mg/mL solution of generic Cosopt See latest prices

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.

How to get Vyzulta without insurance

A person paying cash for a 30-day supply of Vyzulta will spend about $320, so saving money may be a top priority. One place to start is to research any patient assistance program offered by the manufacturing pharmaceutical company, Bausch & Lomb. Unfortunately, not everyone can meet the strict enrollment or eligibility requirements. Manufacturer coupons and rebates are the next logical step, but they’re rarely offered. However, there are other options. At the top of the list is using a savings card from SingleCare.

1. Use SingleCare when purchasing prescription medications

A free coupon from SingleCare can reduce the cost of a 2.5 mL Vyzulta bottle to only $245 at certain local pharmacies. Other participating pharmacies will have different discount prices, so browse the savings on the Vyzulta coupons page. This page includes a FAQ section with additional valuable savings and drug information.

2. Find the lowest price

Considerable savings can be found by comparing pharmacy prices, but that entails making a lot of phone calls. Instead, consult SingleCare’s for an instant overview of average pharmacy prices. 

3. Ask the prescribing healthcare provider about generic prostaglandin analogs

Switching to a generic drug that works like Vyzulta could net significant savings. There’s a chance that other prostaglandin analogs have been tried already. If they haven’t, ask for medical advice about switching to a lower-priced generic. The first-line treatment is usually latanoprost, with an average cost of $80 for a 30-day supply. Generic Lumigan (bimatoprost) and generic Travatan Z (travoprost) are lower-priced alternatives, mainly when purchased at a discount with a SingleCare prescription discount card.

4. Ask the prescribing healthcare professional about combination drugs

It’s common for people with ocular hypertension or glaucoma to take more than one eye pressure drug. The expense can add up when these drugs are purchased separately. Instead, ask the prescriber about combination drugs that include a prostaglandin analog combined with another drug. This may be less expensive than the two medications being purchased separately. 

 

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