Skip to main content
Drug Info

How much is Trintellix without insurance?

Trintellix can be costly without insurance. Learn how to get Trintellix at a lower price, or find cheaper alternatives.
Rx pill bottles: How much does Trintellix cost without insurance

Key takeaways

  • Trintellix is an atypical antidepressant with a high cost for uninsured patients, averaging $566 per month without insurance.

  • Many insurance plans cover Trintellix, but uninsured patients can explore alternatives like SSRIs and SNRIs or use discount cards and patient assistance programs to lower costs.

  • SingleCare offers a discount card that can save nearly $200 on a 30-day supply of Trintellix, significantly reducing its price.

  • Other cost-reduction strategies include asking for generic antidepressants, comparing pharmacy prices with tools like SingleCare’s pharmacy finder, getting health insurance, or enrolling in Medicaid.

Is Trintellix covered by insurance? | How much does Trintellix cost without insurance? | How to get Trintellix without insurance

Trintellix (vortioxetine) is a brand-name antidepressant used to treat major depressive disorder (MDD). Though considered an atypical antidepressant, it acts much like a selective serotonin reuptake inhibitor (SSRI) by balancing chemicals in the brain to give people greater control over mood and thinking. Trintellix is taken as a 20 mg tablet once per day with or without food. There is no generic version or over-the-counter alternatives, but there are many different types of effective generic antidepressants that cost less than Trintellix. Still, uninsured patients have a few options that can reduce the cost of a Trintellix prescription.

RELATED: Trintellix side effects

Is Trintellix covered by insurance?

Many commercial health insurance plans, Medicare drug plans, Medicaid, and the VA cover Trintellix, but some insurance companies may require prior authorization. For most insured patients, however, out-of-pocket expenses will depend on the plan’s formulary, deductible, copay costs, or coinsurance percentage, if any.

How much does Trintellix cost without insurance?

Without insurance coverage, Trintellix can be costly. Patients without insurance can expect to pay the full retail price for a 30-day supply, averaging about $566 per month or $6,800 annually. 

Trintellix can be prescribed as a first-line treatment for depression, but healthcare professionals typically start with similar, more affordable antidepressants such as SSRIs and SNRIs. Like Trintellix, these drugs increase serotonin in the brain, but they don’t attach to serotonin receptors in the brain like Trintellix. If a Trintellix prescription is too difficult to pay for, ask the prescriber about SSRIs and SNRIs. They are widely available in affordable generic versions. If these have already been tried, ask about other types of antidepressants including tricyclic antidepressants, MAO inhibitors (MAOIs), and atypical antidepressants. 

While there are over-the-counter drugs, herbal remedies, and dietary supplements that can help with mood, they are not effective substitutes for prescription medications in the treatment of major depressive disorder.

Compare Trintellix prices to similar SSRI/serotonin receptor modulators

Drug name Price without insurance for brand-name drug SingleCare price Savings options
Trintellix (vortioxetine) $579 per 30, 20 mg tablets $403 per 30, 20 mg tablets for brand-name Trintellix See updated prices
Viibryd (vilazodone) No coupons at this time. Check back periodically More details

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs. The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see updated drug prices.

How to get Trintellix without insurance

Most antidepressants are affordable, but new brand-name treatments like Trintellix can be hard to pay for month after month. Pharmaceutical companies may offer patient assistance programs, rebates, or manufacturer coupons, but there are eligibility requirements and other hurdles to overcome. With some drugs, ordering a 90-day supply is cheaper than purchasing three 30-day prescriptions. Unfortunately, this isn’t true for Trintellix. Fortunately, patient assistance programs and 90-day prescriptions don’t exhaust all the options. Here are more ways to reduce the cost of Trintellix.

1. Start by using a SingleCare savings card

With a SingleCare discount card, people can save almost $200 on a 30-day supply of Trintellix, a nearly 40% price drop. Getting a free Trintellix coupon takes only a few seconds. Go to SingleCare’s Trintellix coupon page and either download or print a SingleCare savings card. The savings card can also be sent to a smartphone.

2. Ask the prescriber about generic antidepressants

There’s a whole armory of effective antidepressants. Most are available as inexpensive generics, affordable even without health insurance coverage. Consider, though, there may be a medical reason a healthcare professional will prescribe an expensive brand-name medication instead of cheaper generics. However, if you can’t pay for Trintellix, it’s better to ask the prescriber for medical advice about less expensive antidepressants.

3. Find the lowest price for Trintellix

All pharmacy prices are not created equal. Finding the lowest Trintellix price could save money from one pharmacy to another, especially when using a SingleCare coupon. Check out SingleCare’s pharmacy finder to find the best prices at pharmacies near you.

4. Get health insurance

Treating depression with antidepressants is a long haul, typically six months to over a year. A year taking Trintellix could cost almost $7,000, so health insurance might be the better deal. Start by visiting your state’s online health insurance marketplace.

5. Enroll in Medicaid

If health insurance is too expensive, look into Medicaid health insurance. Many state Medicaid plans cover Trintellix, but they may require prior authorization. If you meet the income requirements to enroll in Medicaid, the average out-of-pocket cost of a month’s supply of Trintellix is about one dollar. Visit your state’s Medicaid website for eligibility requirements, additional information, and enrollment forms.