How to save on Trintellix: Savings card & more

In this article:

• How much does Trintellix cost?
• How to save money on Trintellix
• Is there a cheaper alternative to Trintellix?

In this article

• How much does Trintellix cost?
• How to save money on Trintellix
• Is there a cheaper alternative to Trintellix?

Trintellix (vortioxetine) is an antidepressant that shifts serotonin levels in the brain to treat adults with major depressive disorder (MDD). Currently, there is no generic version of Trintellix. We’ll outline ways to save on Trintellix, including free SingleCare coupons, a Trintellix savings card, and the Trintellix patient assistance program.

How much does Trintellix cost?

Without insurance, the average retail price of Trintellix is about $660 for 30, 20 mg tablets. The cost will vary depending on your pharmacy, prescribed dosage and frequency, insurance, and other factors.

Many commercial health insurance plans cover Trintellix, and some Medicaid, Medicare, and VA insurance plans may cover Trintellix. Check your insurance company’s formulary list or contact an insurance agent to see if it’s covered. It’s also a good idea to ask about prior authorization—some insurance providers might require it for Trintellix. 

How to save money on Trintellix

Trintellix coupons, the Trintellix savings card, and the manufacturer’s patient assistance program are three ways to save on your Trintellix prescription. 

1. SingleCare Trintellix coupons

SingleCare negotiates with retail pharmacies to help make medication more affordable to patients. 

Best for: Patients who are uninsured or underinsured can benefit from SingleCare coupons, although insured patients can use SingleCare coupons as well—just not in conjunction with prescription drug coverage.

Savings: A free SingleCare Trintellix coupon could save you up to $216 on a month’s supply of Trintellix, costing you around $442 for 30, 20 mg tablets that average around $660 at retail. SingleCare prices vary by form, strength, quantity, and pharmacy. 

Eligibility: All you need is a valid Trintellix prescription and U.S. or Puerto Rico citizenship. You’re still eligible for SingleCare discounts if you’re insured, but SingleCare discounts can’t be combined with insurance copays. 

Get started: Choose your pharmacy from the free SingleCare Trintellix coupon page. You’ll enter your zip code, customize the dosage and quantity, and choose a pharmacy with the best deal. Send your virtual coupon to your phone or email, then show it to the pharmacy when dropping off your prescription.

2. Trintellix savings card

The manufacturer of Trintellis, Takeda, offers the Trintellix savings card for commercially insured patients. Savings card holders can also use tAccess, a support program for Trintellix patients with MDD. The program provides refill reminders, informative notifications, and mobile access to the savings card.

Best for: Patients with commercial insurance—an eligibility requirement—can benefit from a Trintellix savings card.

Savings: Pay as little as $10 for a 30- or 90-day prescription with maximum savings of $100 for a 30-day fill or $300 for a 90-day fill. 

Eligibility: To qualify, you must be 18 years or older with commercial insurance and a valid Trintellix prescription. The savings card can’t be used by cash-paying patients or patients in government-funded healthcare programs (e.g., Medicare, Medicaid, or TRICARE). 

Get started: Register here. Eligible patients will receive an activated online card right away. You can print the savings card or text “TSAVE” to 36395 to download it to your phone. If your healthcare provider gave you a Trintellix savings card, you can activate it using the link above. Once your card is activated, show it to your pharmacist. Call 866‑279‑0287 with questions.

3. Help at Hand patient assistance program

Takeda also offers a patient assistance program called Help at Hand.

Best for: Patients who are uninsured, underinsured, or demonstrate financial need can benefit from Help at Hand. 

Savings: This patient assistance program provides free Trintellix for eligible patients.

Eligibility: You must meet annual household income requirements; be uninsured, underinsured, or struggling to pay for your medication; have a valid Trintellix prescription by a licensed U.S. prescriber; and reside in the United States or a U.S. territory. 

Get started: If eligible, download this application or call 800-830-9159 to get an application mailed or faxed to you. Contact your healthcare provider to start the application. Before submitting it, use this checklist to make sure it’s complete.

Is there a cheaper alternative to Trintellix?

Yes, there are cheaper Trintellix alternatives, but since treatment for MDD is personalized to your needs, there’s no one-size-fits-all alternative. Trintellix is unique because it directly affects serotonin receptors, unlike other antidepressants. Although its active ingredient, vortioxetine, is a selective serotonin reuptake inhibitor (SSRI), Trintellix is an atypical antidepressant. 

SSRIs, serotonin and norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants are other possible treatment options, according to Benjamin Gibson, Pharm.D.  

Lea McMahon, Ed.D., chief clinical officer at Symetria Recovery, shares specific recommendations: “Prozac (fluoxetine), Wellbutrin (bupropion), Lexapro (escitalopram oxalate), and Zoloft (sertraline) are cost-effective, commonly used prescriptions to use in place of Trintellix.”

RELATED: Trintellix vs. Zoloft,│ Trintellix vs. Viibryd 

Remember, your healthcare provider should lead any medication changes. Don’t stop using Trintellix abruptly, due to risks of serious side effects and withdrawal symptoms. In one small study, patients who stopped taking vortioxetine reported discontinuation symptoms, such as agitation, sudden worsening of mood, headaches, and nervousness. Seek advice from your healthcare provider before stopping Trintellix or switching to another medication. 

RELATED: How long does Trintellix withdrawal last?