Soma is an FDA-approved prescription medication that contains the active ingredient carisoprodol, a skeletal muscle relaxant. Limited and low-quality evidence supports the efficacy of muscle relaxants short-term for painful musculoskeletal conditions, low back pain, and chronic spasticity (muscle spasms). It is best used as an adjunct to other measures for relief from these conditions, including rest and physical therapy.
As of 2012, carisoprodol became a Schedule IV controlled substance in the federal Controlled Substances Act based on trends from the decade prior demonstrating drug abuse, carisoprodol overdoses, and it being one of the most commonly diverted drugs according to the Drug Enforcement Administration (DEA).
Is generic Soma available?
Carisoprodol became a prescription drug marketed in 1959 and is widely available as a generic version. Because generic medications are typically less expensive than branded ones, carisoprodol is likely more accessible than Soma.
Carisoprodol vs. Soma: Is there a difference?
Generic and brand-name drugs have the same therapeutic effect, and often, generic drugs are more affordable than brand-name drugs. The main differences between the two include appearance and inactive ingredients, which ultimately may result in different side effects in people if intolerant to certain inactive ingredients. You can always speak to a healthcare provider to dig into specifics related to differences in these inactive ingredients between treatment options.
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Generic Soma cost
The average price of branded Soma without insurance is $268 for 30 250 mg tablets. The average cash price for the generic version is significantly less, around $55 for 30 250 mg tablets.
How to switch from Soma to carisoprodol
No specific changes or precautions are needed when switching from Soma to carisoprodol. The two are therapeutically equivalent and are the same dose on a mg-to-mg basis. However, patients who have been on either brand or generic version of carisoprodol long-term (i.e., beyond the maximum recommended duration of 2 to 3 weeks), should be tapered off slowly over 14 days to avoid withdrawal symptoms, like anxiety, insomnia, or irritability.
In most states, pharmacists can dispense generic carisoprodol for prescriptions written for Soma, with some exceptions. Some exclusions are if the prescriber specifically designates the medication to be dispensed as written (“DAW”) or brand name necessary (“BMN”). Prescribers may designate prescriptions written for brand-name Soma this way when a patient is known to be intolerant to inactive ingredients within generic versions, has an allergic reaction to inactive ingredients, or the prescriber is uncertain about a patient tolerance to a change.
Sources
- Schedules of controlled substances: placement of carisoprodol into schedule IV, Drug Enforcement Agency, 21 CFR Part 1308 (2011)
- Carisoprodol (Trade Name: Soma®), Drug Enforcement Administration (2019)
- Do generic drugs compromise on quality?, Harvard Health Publishing (2021)
- Acute intermittent porphyria, National Organization for Rare Disorders (2022)
- The effects of state-level pharmacist regulations on generic substitutions of prescription drugs, Health Economics (2018).