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How much is lisinopril-hydrochlorothiazide (Zestoretic ) without insurance?

Generic Zestoretic, lisinopril-hydrochlorothiazide, costs $28. Here's how to save on lisinopril-hydrochlorothiazide without insurance.
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By | Jul. 2, 2023 Medically reviewed by Josephine Bawab, Pharm.D.
Rx pill bottles: How much does lisinopril hydrochlorothiazide cost without insurance

Key takeaways

  • Generic lisinopril-hydrochlorothiazide (Zestoretic) costs $28 for a 30-day supply, offering an affordable high blood pressure treatment option without insurance.

  • Most health insurance plans cover generic lisinopril-HCTZ, placing it in their lowest copay tiers due to its common usage and low cost.

  • A SingleCare prescription discount card can significantly reduce the cost of lisinopril-HCTZ for uninsured people, potentially lowering the price to as little as $2 for a 30-day supply.

  • Other options for reducing the cost of lisinopril-HCTZ without insurance include shopping for the best price, enrolling in Medicaid or Medicare Low Income Subsidy, and visiting public health clinics or 340B providers.

In this article:

Lisinopril and hydrochlorothiazide (HCTZ) make up a generic prescription combination drug that is FDA-approved to treat high blood pressure. It combines two types of blood pressure-lowering medications. Lisinopril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) that relaxes and widens blood vessels to lower blood pressure. Hydrochlorothiazide is a thiazide diuretic (“water pill”) that increases the body’s elimination of water. With less water in the blood, blood pressure decreases. Hydrochlorothiazide is often prescribed with other blood pressure drugs, so combination drugs, including hydrochlorothiazide, are very common. As a generic drug, lisinopril-HCTZ is an inexpensive prescription drug, which is good news for people without insurance. The brand-name version, Zestoretic, will cost more.

What is the brand name for lisinopril-hydrochlorothiazide?

Zestoretic is the brand-name version of lisinopril-HCTZ. Compared to the generic version, Zestoretic is more expensive. For people without insurance, the generic version of Zestoretic can be substituted for the brand-name version.

Is lisinopril-hydrochlorothiazide covered by insurance?

Most health insurance plans, including Medicare Part D drug plans, Medicaid, TRICARE, and the VA, usually cover generic lisinopril-HCTZ, but coverage may vary. It is a common and low-cost prescription drug, so insurance companies generally put it in their lowest copay tiers when it is covered. Still, other insurance plans’ policies, such as coverage gaps or coinsurance, will determine the final out-of-pocket cost. 

How much does lisinopril-hydrochlorothiazide cost without insurance?

People without insurance can expect to pay an average of $28 for 30, 20-12.5 mg tablets of lisinopril-HCTZ. This represents a 30-day supply, so a year’s worth of lisinopril-HCTZ will cost over $300 at the full retail price.

As dual blood pressure therapy, lisinopril-HCTZ is one of the lowest-priced treatment options. Taken as separate pills, a 30-day supply of lisinopril and hydrochlorothiazide will cost about $34, so this is not cheaper than taking it as a combination pill. This is usually the case when taking any blood pressure drug separately from a diuretic. Benazepril-hydrochlorothiazide, another commonly used blood pressure combination, costs over $60 for a one-month supply. Generic quinapril-hydrochlorothiazide costs about $50 per month.

Both ACE inhibitors and hydrochlorothiazide are among the cheapest blood pressure medications. Other FDA-approved combination drugs with hydrochlorothiazide will cost more than lisinopril-HCTZ. Examples include losartan potassium-HCTZ ($70 per month) and metoprolol-HCTZ ($60 per month).

Over-the-counter medications, supplements, and herbal remedies are less effective in treating high blood pressure than prescription medications. If considering these as a cheaper alternative to lisinopril-HCTZ, ask a healthcare provider for medical advice first.

The best way to get the lowest price for people without insurance may be a SingleCare prescription discount card. With a free coupon from SingleCare, people can pay as little as $2 for a 30-day supply of lisinopril-HCTZ.
Drug name Price without insurance of brand-name drug  SingleCare price Savings options
Lisinopril-HCTZ $28 per 30, 20-12.5 mg tablets of generic lisinopril-HCTZ $2 per 30, 20-12.5 mg tablets of generic lisinopril-HCTZ See latest prices
Zestoretic

(lisinopril-HCTZ)

 $1,434 per 90, 20-25 mg tablets $2 per 90, 20-25 mg tablets of generic lisinopril-HCTZ See latest prices
Accuretic

(quinapril-HCTZ)

 $192 per 30, 20-25

mg tablets

 $30 per 30, 20-25 mg tablets of generic quinapril-HCTZ See latest prices
Triamterene-HCTZ $40 per 30, 37.5-25 mg tablets of generic triamterene-HCTZ $3 per 30, 37.5-25 mg tablets of generic triamterene-HCTZ See latest prices
Tribenzor

(olmesartan-amlodipine-HCTZ)

 $516 per 30, 40-10-25 mg tablets $46 per per 30, 40-10-25 mg tablets of generic olmesartan-amlodipine-HCTZ See latest prices
Lisinopril $27 per 30, 10 mg tablets of generic lisinopril $2 per 30, 10 mg tablets of generic lisinopril See latest prices

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.

How to get lisinopril hydrochlorothiazide without insurance

Lisinopril-HCTZ is among the most affordable hypertension drugs for uninsured people. However, it is an ongoing expense and will quickly add up to over $300 in a year. Patient assistance programs and manufacturer coupons often help save money on premium-priced brand-name drugs, but they are rarely offered for generic drugs. This means that the first place to look for savings should be SingleCare’s prescription savings program.

1. Get discounted prices with a SingleCare savings card

At SingleCare-participating pharmacies, a free SingleCare coupon can lower the cost of lisinopril-HCTZ to as low as $1.64 for a 30-day supply. SingleCare discounts vary by pharmacy, so shop for available savings at local pharmacies on the lisinopril-hydrochlorothiazide coupons page. Be sure to read through the FAQs section for additional savings and drug information about lisinopril-HCTZ.

2. Shop for the best price 

Prescription drugs are like all retail goods—prices vary depending on where medications are purchased. The lowest price for lisinopril-HCTZ is $8, a full $30 less than the highest pharmacy price of $38. Finding big savings like that can further reduce the price of lisinopril-HCTZ.

3. Enroll in Medicaid

If paying the cash price for generic drugs is burdensome, Medicaid may be an option. Premiums, prescription drugs, office visits, tests, and procedures have minimal out-of-pocket expenses. However, there are income limits and other requirements. Find out what these are by visiting your state’s Medicaid website. 

4. Enroll in Medicare Low Income Subsidy

For seniors, Medicare Low Income Subsidy—or simply Medicare Extra Help—is the Medicare equivalent of Medicaid. Eligibility requirements will be very similar to Medicaid. A local healthcare department can help with requirements and enrollment. 

5. Visit local public health clinics or 340B providers

Other valuable resources for people without health insurance are public health clinics, community clinics, and 340B providers. They may be able to provide services and prescription drugs at a low cost or for free. If you don’t know where to start, staff at a local healthcare department can help.

 

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