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Key takeaways
Imvexxy is a brand-name prescription drug used to treat painful sex due to menopause, costing $303 for a 30-day supply without insurance.
There are no generic equivalents to Imvexxy, but other vaginal estrogen products may offer lower-cost alternatives.
Imvexxy may be covered by some insurance plans, but uninsured patients can save through manufacturer savings programs or using a SingleCare savings card.
Alternatives to Imvexxy include various forms of vaginal estradiol and synthetic estrogen hormones, potentially offering more affordable treatment options.
Imvexxy is a brand-name prescription drug for women that treats moderate to severe painful sex (dyspareunia), a symptom of the thinning and drying of vaginal and vulvar tissues after menopause. Inserted into the vagina twice per week, the Imvexxy vaginal insert releases low doses of estrogen estradiol onto the surfaces inside of the vagina. By supplying estrogen directly to the vaginal lining, Imvexxy improves the health of vaginal tissues, the elasticity of these tissues, and vaginal lubrication. As a brand-name drug, Imvexxy is more expensive than generic estradiol. Uninsured women who are prescribed Imvexxy, however, have opportunities to save on their prescription or choose lower-priced alternatives.
What is the generic version of Imvexxy?
Imvexxy is a brand-name drug with no generic or over-the-counter equivalents. However, there are other vaginal estrogen products including inserts, rings, and creams that can deliver estradiol or another estrogen to vaginal tissues. Some are lower in price than Imvexxy but may not deliver the same dosage.
Is Imvexxy covered by insurance?
Imvexxy is covered by some health insurance plans, but most Medicare Part D prescription drug plans and Medicaid plans may not cover it. The insurance plans that do cover Imvexxy provide coverage for both the starter and maintenance packs, but they may have restrictions or need prior authorizations before covering them. Most insurance companies that cover Imvexxy classify the drug in their higher drug tiers, so the out-of-pocket cost may be higher than other covered drugs. Women with commercial health insurance coverage for Imvexxy may be eligible to use the Imvexxy Savings Card from TherapeuticsMD to reduce the monthly copay cost.
How much does Imvexxy cost without insurance?
Without insurance, the Imvexxy Starter Pack will cost $543 for 18 vaginal inserts (or $30 per insert), and each 30-day supply of Imvexxy Maintenance Pack after that will cost $303 for 8 vaginal inserts (or $38 per insert). The dosage prescribed (4 mcg or 10 mcg per insert) will not affect the final price. At these prices, pharmacy customers without insurance can expect to pay about $3,800 for the first year of treatment and slightly less than that for each year after.
While Imvexxy has no exact equivalent, women do have other treatment options. Vaginal estradiol can be prescribed in the form of inserts, creams, or rings. Some of these products may be FDA-approved for other conditions, such as vaginal atrophy, vaginal dryness, or vaginal bleeding. Some may have higher or more erratic dosages. Most are brand-name products, but estradiol cream can be purchased as a generic.
Estradiol tablets may be an option, but they are not the best one. Oral estradiol has potential dosing issues and the risk of serious side effects, such as breast cancer, endometrial cancer, blood clots, and heart attack.
If price is an issue, get medical advice from the prescribing healthcare provider about these alternatives.
RELATED: Imvexxy alternatives: What can I take instead of Imvexxy?
Compare Imvexxy (estradiol vaginal) prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Imvexxy starter pack | $543 per 1 box of 18 inserts | $402 per 1 box of 18 inserts of brand-name Imvexxy | See latest prices |
| Imvexxy maintenance pack | $303 per 1 box of 8 inserts | $181 per 1 box of 8 inserts of brand-name Imvexxy | See latest prices |
| Estradiol | $21 per 30, 1 mg tablets of generic estradiol | $3 per 30, 1 mg tablets of generic estradiol | See latest prices |
| Estrace | $426 per 42.5 gm of 0.1 mg/gm cream | $17 per 42.5 gm of 0.1 mg/gm cream of name-brand Estrace | See latest prices |
| Intrarosa | $276 per 1 box of 28 inserts | $221 per 1 box of 28 inserts of name-brand Intrarosa | See latest prices |
| Vagifem | $224 per 1 box of 8 vaginal inserts | $134 per 1 box of 8 vaginal inserts of name-brand Vagifem | See latest prices |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.
How to get Imvexxy (estradiol vaginal) without insurance
Paying for a brand-name prescription drug without insurance can be challenging. Still, even without insurance, there are ways to reduce the price of prescription drugs or get similar drugs at a lower cost. One alternative for brand-name drugs like Imvexxy is to see if the manufacturer offers a savings program or manufacturer coupons. The problem is that these are not always available. When they are, people may not be able to meet strict eligibility requirements. It’s worth a try, but more dependable savings are out there, starting with a SingleCare prescription discount card.
1. Save $1,400 a year on Imvexxy with a SingleCare savings card
Pay a discount price of $402 for the Imvexxy Starter Pack (or $22 per insert) and $181 for the Imvexxy Maintenance Pack (also $22 per insert) in the following months with a free Imvexxy coupon from SingleCare. The first year of treatment could cost $2,400—a $1,400 savings off the average retail price.
2. Shop for the lowest price
Different pharmacies charge different prices for the same prescription medications. You may call your local pharmacies to compare prices or use the SingleCare website or app to compare discounts. Find a participating pharmacy near you here.
3. Ask for a free sample
The prescriber may have free samples of Imvexxy for you to try. Each free sample contains two vaginal inserts, which is enough medicine for one week of maintenance therapy. This isn’t a sustainable savings method for a recurring Imvexxy prescription, but at full retail cost, one week of Imvexxy is worth more than $60.
4. Ask the prescriber about other treatment options
Imvexxy is not the only estrogen that is administered vaginally. Generic estradiol vaginal cream, Estrace vaginal cream, Vagifem vaginal inserts, and the Estring vaginal ring are all estradiol products that can be used instead of Imvexxy. Most can be purchased for less than the price of Imvexxy. Estradiol vaginal cream is the least expensive. With a SingleCare discount card, a tube of estradiol vaginal cream can be purchased for less than $2, depending on the pharmacy.
There are also synthetic estrogen hormones that are applied vaginally. There are differences, however, between these drugs and Imvexxy. Start by asking the prescribing healthcare professional about the pros and cons of switching to other estradiol products.