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Drug Info

Cialis generic availability, cost, and dosage

Brand-name and generic Cialis are essentially the same medication with the same active ingredient
Rx prescription pad & Rx pill bottle: Generic Cialis

Key takeaways

  • Generic Cialis, known as tadalafil, became available in the United States in 2018 after Eli Lilly’s patent expired, offering a lower-cost alternative for treating erectile dysfunction (ED) and benign prostatic hyperplasia (BPH).

  • Cialis and its generic version, tadalafil, are phosphodiesterase-5 enzyme (PDE-5) inhibitors used to treat ED and BPH by improving blood flow and relaxing the muscles in the prostate and bladder.

  • While brand-name Cialis and generic tadalafil contain the same active ingredients and are equally effective, their appearance and cost may vary, with generics typically being more affordable.

  • Transitioning from Cialis to generic tadalafil should be done under the guidance of a healthcare provider, with doses being identical and based on individual needs, to ensure a safe and effective switch.

Cialis, also known by its generic name, tadalafil, is a medication commonly prescribed for erectile dysfunction (ED). It is also approved to treat benign prostatic hyperplasia (BPH), or an enlarged prostate. 

As a phosphodiesterase-5 enzyme (PDE-5) inhibitor, tadalafil helps improve blood flow to the penis to maintain an erection. It works by blocking the PDE-5 enzyme to prevent the breakdown of a molecule called cGMP, which is involved in relaxing the blood vessels. 

Cialis was initially approved in 2003 and has become a popular alternative to Viagra (sildenafil). It stands out as an as-needed ED medication that can also be used daily to treat an enlarged prostate. The medication is widely accessible as a brand-name and generic drug that can be purchased from retail pharmacies across the nation. 

Is there a generic for Cialis?

Yes, there is a generic version of Cialis available called tadalafil. Generic Cialis became available in the United States after the exclusivity patent for Cialis, held by Eli Lilly, expired in 2018. As a generic medicine, tadalafil offers the same benefits and uses as Cialis but typically at a lower price. It may be an appealing choice for those seeking treatment for ED and BPH. 

Teva Pharmaceutical Industries were the first to release a generic Cialis tablet in 2018, with several pharmaceutical manufacturers following suit. Now that generic tadalafil is available, people with ED and BPH may have more options when it comes to managing their symptoms and finding relief.

What is Cialis used for?

Cialis is a prescription medication that should only be used as directed by a healthcare provider. The following are the common uses of Cialis.

Erectile Dysfunction

Cialis is FDA-approved for ED and BPH. ED occurs when a man has difficulty achieving or maintaining an erection that is sufficient enough for sexual activity. Cialis helps increase blood flow to the penis during sexual stimulation. It is typically taken at a dosage of 5 to 20 mg as needed before sexual activity, with effects that can last for up to 36 hours.

Benign Prostatic Hyperplasia

Another FDA-approved use of Cialis is the treatment of BPH, which is characterized by an enlarged prostate. Symptoms of BPH may include frequent urination, difficulty in starting to urinate, and a weak flow of urine. Cialis works by relaxing the muscles in the prostate and bladder, improving urine flow. It is approved for daily use for treating BPH or BPH and ED. 

Other uses

Tadalafil may be prescribed as a generic or under a brand name called Adcirca for individuals with pulmonary arterial hypertension (PAH). An individual with PAH experiences high blood pressure in the arteries of the lungs, which can cause chest pain, shortness of breath, and fatigue. By widening the blood vessels, tadalafil can lower the blood pressure in the lungs and improve the capacity to exercise in people with PAH.

In addition, Cialis or tadalafil may be used off-label for the prevention of altitude sickness, which can occur when individuals ascend to high altitudes too quickly. Symptoms of altitude sickness include headaches, nausea, and shortness of breath. Tadalafil may help improve oxygen supply and blood flow throughout the body. 

What are the differences between brand-name and generic Cialis?

Brand-name and generic Cialis are essentially the same medication with the same active ingredient. Although they share the same therapeutic effects, they may have some differences. 

Appearance

One noticeable difference between brand-name Cialis and generic tadalafil is their appearance. Brand-name Cialis has an unmistakable yellow, almond-shaped design, while generic tadalafil may differ in color, size, or shape depending on the manufacturer. However, this difference in appearance does not affect the medication’s efficacy or safety.

Dosage forms

Both brand-name Cialis and generic tadalafil come as oral tablets in identical strengths, such as 5 mg, 10 mg, and 20 mg tablets. Both generic and brand-name versions can be taken orally, either as needed before sexual activity or once daily, depending on the condition being treated.

Effectiveness

Regarding effectiveness, studies have shown that generic medications are just as effective as brand-name drugs. Both brand-name and generic Cialis work by increasing blood flow to the penis, resulting in a firmer and longer-lasting erection. Due to the similarity in their active ingredients, both versions are effective for ED and BPH symptoms. However, a healthcare provider may recommend the brand-name version of the generic for any number of reasons, such as potential allergies to ingredients or their own beliefs about generic drugs. 

Cialis (tadalafil)
Uses
  • Erectile dysfunction
  • Benign prostatic hyperplasia
Standard dosage
  • ED: 5–20 mg before sexual activity
  • BPH: 5 mg once per day 
  • BPH and ED: 5 mg once per day 
Common side effects
  • Indigestion
  • Back pain
  • Muscle aches
  • Stuffy or runny nose
  • Flushing 
  • Headache
Contraindications
  • Avoid use with nitrate drugs, such as nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate
  • Allergies to tadalafil or other ingredients in the medication
Other considerations
  • Tadalafil may cause a sudden decrease in blood pressure, especially when combined with nitrate medications, alpha-blockers, antihypertensives, or substantial amounts of alcohol
  • Tadalafil is not recommended in combination with alpha-blockers for the treatment of BPH, due to a lack of data on effectiveness and the potential risk of severely low blood pressure
  • Seek immediate medical attention if an erection lasts longer than 4 hours, as this can lead to permanent damage
  • Discontinue Cialis and seek immediate medical attention in case of sudden vision or hearing loss
  • Before starting treatment with Cialis for BPH, other urological conditions that may cause similar symptoms should be ruled out
  • People with heart problems or those who have had a recent heart attack should use Cialis with caution, as sexual activity may put additional strain on the heart
  • Always consult with a healthcare professional for proper dosage and potential drug interactions
  • Monitor for signs of an allergic reaction when taking tadalafil, including rash, hives, swelling of the lips, tongue, or throat, or difficulty breathing or swallowing

Both the brand Cialis and the generic versions have the same active ingredients. However, their appearance and costs can vary. Therefore, you may want to talk to your doctor or healthcare provider to determine the best option for you.

How much is generic Cialis?

Generic Cialis is usually a more affordable option than the brand name. The price of generic Cialis may vary depending on your location, insurance coverage, and the specific dosage needed. While Medicare and commercial insurance plans do not generally cover the brand-name version, some plans may cover the generic version. In many cases, insurance does not provide coverage for Cialis when used for ED, but only when used for BPH.

The price difference between branded and generic Cialis can be significant, and choosing the generic version could potentially save you money. Using a prescription discount card, such as the one from SingleCare, may help reduce the retail cost of Cialis and other prescription drugs. 

Brand vs. generic Cialis prices

Brand-name Cialis Cialis generic (tadalafil)
Average cost without insurance $453 for 30 tablets of Cialis $319 for 30 tablets of tadalafil
SingleCare’s lowest price $7 for 30 tablets of generic Cialis $7 for 30 tablets of tadalafil
Free coupons Cialis coupons Tadalafil coupons

Keep in mind that prices may vary due to factors such as pharmacy location, insurance plans, and availability of discounts or coupons. It’s always a good idea to compare prices and explore different pharmacies to find the best option for your individual needs.

How to switch from Cialis to tadalafil

Switching from the brand-name erectile dysfunction medication Cialis to its generic counterpart, tadalafil, should be done with guidance from your healthcare provider. In most cases, a pharmacist can dispense the generic version if the prescribing doctor does not indicate the brand name is medically necessary. The following steps outline this process and offer helpful tips for a safe transition.

Transition process

  • Start by consulting with your healthcare provider. They can provide medical advice, assess your health, symptoms, and determine the appropriate starting dose for tadalafil. The doses for Cialis and tadalafil are identical and should be based on individual needs and the provider’s prescription.
  • To avoid disrupting your medication schedule, take the first dose of tadalafil at the same time you would typically take your Cialis dose, or as directed by your healthcare provider. 
  • Both Cialis and tadalafil have the same active ingredient and similar side effects. During the transition, monitor for any serious side effects and report persistent or worsening symptoms to your healthcare provider.

Be aware of fake Cialis pills

The prevalence of counterfeit Cialis, particularly online, has become a major concern for consumers. Fake Cialis can pose serious health risks as it may not contain the correct strength and proper ingredients, or it might be contaminated with toxic ingredients. That’s why it is often recommended to only buy genuine Cialis from reputable sources.

When ordering Cialis online, you may want to choose an accredited online pharmacy that requires a prescription. Avoid pharmacies that do not provide enough information about their products, as they may sell counterfeit or unsafe medications. You can also check for certifications and customer reviews on pharmacy sites before making a purchase. For added security, consider using mail-order pharmacies recommended by your insurance provider. 

Fake Cialis pills often have a different appearance than genuine Cialis. Authentic Cialis tablets should be yellow or orange-yellow, almond-shaped, stamped with the letter ‘C’, and sealed in a branded blister pack. Suspicious tablets may come in different colors or shapes and lack the proper dosage markings. By being vigilant and staying up-to-date, you can reduce the risk of purchasing and consuming counterfeit Cialis.